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Dan Doctoroff

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37
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2023-11-16
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2023-11-16
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  1. No material regrets. But then at the end of the day, I found that what's key to life is relationships and they have a purpose. And my purpose right now is all about eradicating ALS. And that's what I decided to segregate my life to when I was diagnosed. And it was obvious to me. So relationship's purpose is really what life's all about. And by the way, I've been having a good time too. Oh, good. I feel less pressure. I spend more time traveling, seeing people I care about. And that's also makes me happy.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  2. I just do. I've explored a lot about why I'm so happy. And yes, there's a lot of bad things going on in the world, but everything else going on in the world. But, you know, with a limited lifespan, I tried to analyze why I have been so happy. First, I don't think about the future that much of with the exception of ALS. Secondly, you know, I've been surrounded by so many people who've been so loving and supportive. Third, I'm grateful for. My life. You know, I've had a great life. My white Elise and I've been together 46 years with three wonderful kids, two grandchildren. I have a lot of friends. I've done what I wanted in my career and outside my career. And so I don't have any regrets.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  3. I don't think he has any interest in politics. That's not say he can't be helpful to candidates that he believes in. But I have to say about Mike, I spend 13 years working for him six in City Hall. And seven at Bloomberg, where I was the CEO. And Mike's one of the great people. On the planet today, I'm on the board of Bloomberg Philanthropies. They do incredible work. But as a leader, he was the ideal leader for New York coming out of 9-11.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  4. Well, I don't know enough about the progress that's been made, but I will say having a rat sour is very impressive. And by the way, Bert Bloss, Jessica Tish, who's a sanitation commissioner, is a star.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  5. I love Channo. Jano, I've worked together on the rebuilding of the World Trade Center site. He was the number two. Till Larry Silverstein, we had huge fights, but we've respected each other. And I think he is doing an amazing job. I think he's been a great leader for the MTA.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  6. I really like Kathy, Governor Hokele. She is dealing with a very difficult legislature. She's more moderate than the Assembly or Senate. The biggest problem New York has is a lack of housing. New York's economy grew, but we didn't add enough housing. And so housing costs have gone up. And despite the fact that, which is a mystery to me, that we've lost some people during COVID, the apartment rates at Ascalated. This month The state legislature has been very difficult and has been reluctant to agree to an incentive program to build housing. We have said it in New York City that we have to build 500,000 units of housing in the next 10 years statewide it's 800,000 and without cooperation from the state legislature it's not going to be possible

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  7. I think he's inspiring. I think he is the right philosophy. He focuses on crime and quality of life issues. He believes in business that drives a large part of the tax base. But I don't think people have yet been convinced that it can execute. I'm not saying he can't, but we need to demonstrate that he can.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  8. Up until COVID, 18 years. New York added a million new jobs. It was almost twice the rate of new job production that the rest of the country had. We had neighborhoods that blossomed in ways that no one ever would have imagined in the Bronx, we had a huge increase in the normal business. In Brooklyn, it increased the Bloomberg administration by almost 50% the number of business formed compared to prior at Queen's Staten Island. In fact, the only area that did have an increase in the number of new bits formations was Van. So it's all about inspiring confidence.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  9. Yeah, look, you have to have ideas. The idea that inspired people to empathize, but people are not going to be inspired to and fast unlike people are convinced that you can execute and make the city better and better. Going back to that virtuous cycle that I talked about is that Every city needs investment. But every city needs in confidence that they can execute in order to get people to invest. You know, in the 20 years.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  10. And so we need to get them to work I probably would have registered the migrants according to the federal regulations and just let them work.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  11. Wow, the big issue is let's the number of people by getting them to work. And the federal government has been pretty inflexible until recently by allowing migrants to work. But if we can get them to work, then they'll earn money, they'll move out of shelters. But it's all about economic mobility. Immigrants for New York, it's always been a driver of growth. But if you limit their activities, They're drain

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  12. I think in New York it's dramatic. Everywhere in the country, crime escalated through COVID. If you look at New York, for example, murders are down over the last couple years. We still have property crime issues that need to be addressed. But New York is still reasonably safe. We've seen crime drop on the subways as well. But we have much more to do. We're not back to the battle days by any search of the imagination.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  13. Well, again, it's about quality of life. But I led a commission, co-led a commission, put the mayor and governor in 2022 to think about strategies to Read build the city, particularly Midtown and Downtown. And there were three major components to it. You've got to create in Midtown and downtown a more vibrant 24-7 community. So converting Olaf buildings to residential is critical. Being able to build Higher apartment towers is critical. Having entertainment and things on the streets and new attractions is critical. Being able to adjust zoning so that there can be more and different businesses, what you want is just to attract more people for more hours of the day in these districts.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  14. neighborhood dramatically greater um and so we've seen a shift From the activity levels in Midtown and downtown to other neighborhoods.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  15. I think that's to some extent overblown. I've seen statistics a couple thousand people actually left. Some of them were very wealthy, and that had an impact on the tag space. The big issue is the issue on commercial real estate. People don't need as much space because people work from home. The business around the office buildings are less busy than they were. But that's mostly in midtown and downtown. If you actually look at the activity level, the people on the street throughout the rest of the city

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  16. Well, I think obviously COVID and return to work, we don't know exactly where the trends will go. But I'm an optimist about the cities. I think people want to be together. But at the end of the day, you have to have a quality of life, starting with safety. That induces people to come. I was always opponent of what I call the virtuous cycle of the successful city, that you wanted more people running more residents, more jobs, more visitors, because the marginal benefit from a revenue perspective of those additional people was greater than the marginal costs. And you could reinvest Please smartly. The additional revenues back into quality of life as quality of life improves, more people come and the cycle perpetuates.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  17. Yeah, look, I think experimentation is good. No one's forcing people to live there. Down the other end, they're always political issues in terms of It's got to be a partnership between government and the private sector. And that book, by the way, was our whole philosophy in New York City government after 9-11.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  18. Yeah, I think the perception of tech, big tech, certainly didn't help. But I think at the end of the day, we withdrew because we didn't feel like we were going to be able to get through the innovations through the governments and we were dealing with three levels of government. And it just wasn't worth it to spend all this time and end up with something that wouldn't be a huge advance. So we withdrew.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  19. This was a 12-packers sighting, which is experimental, where everyone would choose to live there. And we thought we could teach the world about how do we evolve using technology. And it was a partnership between government and a private company and that it would be controlled. Experimentation is critical, but experimentation. under the right conditions, I think is also critical. And we were totally open to having government as a partner.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  20. Yeah, because we had proposed. System, you know, the use of data in public space is not ever regulated. There are cameras everywhere. And it's never regulated. We had proposed a system of government control where they would dictate every use of the data. And we would live with it. So again, I think it was completely overblown.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  21. We created a company called Sidewalk Infrastructure Partners, which uses digital technology to enhance infrastructure. We created a company. Called Mesa, which enabled easy retrofeds with sensors and things to lower the energy consumption in Class B and C building. A company called DAL. Which is a new way of planning projects using AI and machine learning. So a lot of companies came out of

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  22. Yeah, our proposal was less about privacy and digital stuff than it was about mass timber buildings, getting to climate positive. Moving people around in different ways, doing new approaches to public space. A lot of the criticism up in Canada was focused on privacy, but the reality was we weren't going to use data in what people thought we were. I think that was an overdone excuse for a lot of people who didn't want the project to go forward. But out of it, we developed a series of companies that continue, giving an example City Block Health was an idea that came out of The explanation, exploration of what we could do socially and Citibloc, which, by the way, in four years achieved a $6 billion valuation, is all about finding a new approaches to care for the urban poor in a different way.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  23. Well, I think what momentum attracts attention, and because there's been so much progress in ALS research over the last 10 years, they're building momentum and people believe, these companies believe that the disctable, that it'll be solvable, and that they can make money from it. And so they wouldn't do it unless both of those conditions

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  24. For the first time ever, we've seen symptoms referred. And patience. Now it's for a very narrow set of genetic mutations, but it's pretty remarkable that Something that nobody ever would have thought was possible five years ago. This happened. We have a series of clinical trials underway. And again, I'm convinced that a clinical trial I've been in has extended my life.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  25. Alzheimer's, Parkinson's, Huntington's. There's a lot of overops who would partner with other diseases as well. And that strategy has been phenomenally successful. We funded 60 consortia over the last 10 years, Target Alice was formed in. 2013

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  26. IP issues were laced throughout, which slowed everything down. And so we decided to form target ALS, which would remove all those barriers. And so what we do is we fund multidisciplinary cross-sectoral consortia of researchers on important ALS topics, why do motor neurons die, what do we do about it. We also fund research tools that anybody in the world can use for free that are critical to advancing research. We focus on bringing industry And to the field by involving them in everything we do, we partner with other related diseases because ALS has a lot in common with other neurodegenerative diseases.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  27. So after my uncle died, which was after my father died, I decided, you know, it's so personal. I assumed it was hereditary in my family. I had to do something. So what I did is I brought together a small team of scientists because there really hadn't been much progress in ALS research since the disease was discovered in 1870. And this was after 2010. And they developed a set of hypotheses About why there was so little progress. It was about funding, barriers to entry to do scientists getting involved in the field, the lack of industry involved in the disease.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  28. Yeah, but before she was born, while I was being diagnosed, I think to myself, this is so terrible. I'm probably not going to live to see her turn five. And once I was diagnosed, once she was born, I never think that way. I just revel in her growth and development. And I just looked being with her because I'm in the moment. It's also changed me. I'm definitely much more patient than it was. I'm not.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  29. So when I was diagnosed, something flipped in me and I Stop thinking pretty much about the future, with one exception. I'll get back to that. But I don't think about the future course of the disease much. I've changed pretty dramatically that I live pretty much day to day. Which is phenomenal. And I do think, and it's speculation, but my natural optimism leapt in to protect me somehow. Because if you do think about the future course of this disease, it can be really debilitating. But I don't. I'll give you an example. My granddaughter was born on the weekend I was diagnosed.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  30. No. Something happened to me when I was diagnosed. As you point out, I've always been so focused on the future. In fact, I've been so focused on the future that I never took time to appreciate any of the things that I achieved because I was always on to the next thing.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  31. I went to see two of them and they tested me doing all sorts of different tasks, breathing tasks, strength tasks, tests of my muscles and how they react to shocks. And they both concluded that almost certainly I had ALS. And yet the genetic testing still hadn't come back. My primary symptom, not the exclusively, is breast. The disease has really attacked my diaphragm first.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  32. But we climbed about. And I was exhausted. And I'd just been biking two weeks before and I was fine. Then it followed a kayak. And it tried to get back in. And it felt like I was suffocating. It was just very weird. And so when I came back, I didn't think it was ALS or anything. I went to a doctor who had treated me for a back problem, and he noticed that my body was twitching, which is a symptom of ALS. And he called in the head of durology at the hospital. And he just looked at me and said he knew my family history that I had a six in ten chance of having ALS. Pretty astounded by that because I formed an ALS research foundation and knew the leading clinicians and researchers in the field.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  33. You know, I said I didn't want to be tested. They didn't want to tell my kids. But had I been tested, I would have had a full sense of security and relief

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  34. Well, we don't know for sure because there are a number of people who don't have the mutation, but have a parent that does. And it's much more than... The random odds of having ALS. So there's something else going on, but we haven't figured it out yet.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  35. How you came to terms. My dad, my uncle, and actually their first cousin, all had the same genetic mutation that causes ALS or frontotemporal degeneration, which is the disease that Bruce Willis was just diagnosed with. The ALS and FTD are on the same clinical spectrum. So I never wanted to be tested because there wasn't a cure. And if I tested positive, I would have to tell my kids. And I didn't want to do that. So two years ago, I was diagnosed in a complete shock to me. And then the genetic testing came back, and I do not have the same genetic mutation that my father, uncle, and their first cousin had. I have some other cause. Of ALI, which is to this day still a mystery.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  36. Yeah. So ALS is a disease of the motor neurons. And those are special cells in your brain and spinal cord that send signals to the muscles to move. And for a variety of different reasons. Those motor neurons die. And when they die, they can't send the signals to the muscles to move. And so the patient gets increasingly paralyzed. And what eventually kills the patient is respiratory failure because the muscles that help you breathe don't work anymore. The average patient And this is really tragic, dies within three to five years after diagnosis. Some people ask obviously longer, like Stephen Hawking. But we're making incredible progress toward treatments. We're not there yet, but we are baking incredible progress.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT

  37. I'm doing great. You know, it's two years since I was diagnosed. And I'm still pretty independent. You know, I'm progressing, as they say. My hand doesn't work so well. My foot, my hip, my breathing is labored. But I really haven't had a bad day since I was diagnosed. It's good to be an optimist.

    2023-11-16 · On with Kara Swisher · Dan Doctoroff on Living with ALS and Building the Future · IDENTIFIED FROM THE TRANSCRIPT