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Dr. Gül Dölen

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110
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2023-04-19
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2023-04-19
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  1. By and large are not social species. So two octopuses of the same species into a tank together, they will kill each other. And there are, you know, differences in the amount of aggressiveness that we observe in octopuses. Some are so aggressive that we've never even seen the males of the species because when they mate, they like leave their hectacotylous arm, which is their reproductive arm in the mantle of the female and eject it and escape so that they don't get eaten. So we've only ever found their hectacotylous arm. That's how aggressive that species is. So other species of octopus aren't quite so aggressive, but they're still asocial. And it was interesting.

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  2. Those were actually not my experiments. Those were experiments done by really imminent octopus researcher Roy Caldwell. And he showed me the videos of them. And as soon as I saw the videos of the octopuses hunting, it occurred to me that that is exactly a theory of mind-like behavior in an octopus. And the reason that that was so interesting is because the way that people talk about theory of mind is that this is a behavior that evolved due to the selection pressures imposed by social living. So when we have to live in a social group, it serves us to be able to anticipate what other members of that social group might be thinking in order to anticipate and either compete or collaborate or whatever it is that you're trying to do.

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  3. Somewhere. And so I like this idea that we could test the requirement of theory of mind for consciousness by looking at diseases where that function is impaired and learn something about the relationship between consciousness and genes that encode different proteins that are required for that theory of mind.

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  4. Trying to get. And so this theory of mind idea was sort of out there and there was some idea that, well, you need to have theory of mind in order to have consciousness, in order to have a full sense of knowing who you are compared to other people. And I like this idea because it was a testable hypothesis. And one of the things that I found sort of frustrating about being a philosopher is that the philosophers were always asking the coolest questions, the biggest questions, but just felt like, you know, they were just going around in circles and never really coming up with an answer that I found to be deeply satisfying. And on the other hand, you know, scientists, neuroscientists, you know, maybe they weren't getting to ask all the really big questions, but man, they were coming up with some concrete answers that felt tangible and like we were getting.

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  5. They'll reach around your back and tap you on the wrong side and look the other way. And that's them sort of playing with the idea that their own point of view and the person whose shoulder they're tapping might be different and that they can trick somebody by playing on that difference. And so this theory of mind, there was some idea out there, you know, I'm not sure that it's really a dominant theory right now in autism, but there was an idea that this is something that people with autism are not so good at. And it makes them bad poker players, it makes them bad at lying, it makes them bad at tricking people. It's this thing that psychopaths, for example, are very good at. They have better than average theory of mind, and they use that better than average theory of mind to manipulate people by anticipating what they may or may not like and using that information to try and get whatever it is that they're

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  6. Theory of mind, which is not really a theory in the way that we have a theory of light or a theory of synaptogenesis or any of the more commonplace theories, it's more like it's a point of view. The shorthand way of explaining what theory of mind is that I like to tell people is it's sort of what you're doing. It's the neurobiological process that is going on when you're playing poker. It's anticipating what somebody else might be thinking and trying to see the world from their point of view. So in some sense, it's a theory about what somebody else might be thinking. And this ability to understand or to have a concept of what somebody else might be thinking is something that we develop and we get better at as we mature. So you can always tell when a kid is starting to pick up theory of mind, it first comes on around age four or five because they start doing these funny pranking behaviors where

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  7. Philosophy of Mind, it's not really a branch of philosophy or anything, it's just a thing that has drawn the attention of philosophers from a variety of different perspectives. Like you can imagine considering what is the mind from a metaphysical point of view. So what are the things that we count when we say this is what a mind is, this is what a mind is not. Then there are other considerations like, well, how do we know mind? You know, can we know mind just through introspection or is there some empirical way or some way that we can compare different people's descriptions of those things to get at what is mine? And that would be sort of the more epistemological approach to mind. And I was interested in all of those things. There continues to be debate about that. And one of the interesting ideas that I came across was that there was this concept.

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  8. Have to say, I'm not really sure why exactly those. It just, compared to everything else that I saw other people majoring in, you know, like economics or history, I just didn't care about those things the same way as I cared about. I just found myself, I've always wanted to only study or think about things that I think are deeply interesting that I would want to talk to with anybody, whether it be the person sitting next to me on the bus or my parents or somebody's kid. You know, I just, I like thinking about things. And when I'm obsessed with something, I just think about it all the time in every context. And so I just never had that with economics or history or any of the other topics that seem to be popular majors.

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  9. Linguistics, art, religion, and really the idea was that this is something that humans care about. And so we've thought about it from all of these different perspectives for millennia and what can we understand from that approach.

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT

  10. I've always been somebody who learns best by comparing. And originally I thought, well, I'll just do a triple major of neuroscience and linguistics and philosophy. And the university was like, no, no, there's no triple major. You can do a double major, but if you really need all three, we recommend that you do this design your own major path. And so I worked with my professors in philosophy and neuroscience primarily to come up with a curriculum that would span all of the different elements that I wanted to incorporate in trying to ask the question, what is the mind? What is consciousness? How do we know that from different perspectives? And so the major was called comparative perspectives on the mind, and it was a combination of neuroscience, philosophy.

    2023-04-19 · The Tim Ferriss Show · #667: Dr. Gül Dölen on Rethinking Psychedelics, New Applications (Autism, Stroke, and Allergies), The Neurobiology of Beginner’s Mind, Octopuses on MDMA, and The Master Key of Metaplasticity · IDENTIFIED FROM THE TRANSCRIPT