YouSaid · the spoken record

Stéphane Bancel

lines on the record: 31
first: 2022-05-31
most recent: 2022-05-31
sittings or episodes: 1
sources: podcast

Every line below is reproduced as it was said and linked to the record it came from. Nothing here is summarised or generated. Directory · Search · Corrections

“Master to scale is a Wakewater Original. Our executive producers are June Cohen, Darren Triff, and Jordan Cloud, our head of content and production is Lori Hoffman. Our producers are Adam Skeuse, Catherine Clark Gray, Marie McCoy Thompson, Alex Morris, Tucker Ligurski, and Holly Bondi. Our editor at large is Bob Saffian. Our music director is Ryan Holliday. Original music and sound design by Eduardo Rivera. Audio editing by Keith J. Nelson, Stephen Davies, Andrew Nalt, and Mike Gallagher. Mixing and mastering by Brian Pugh. Special thanks to Chriche, Elisa Schreiber, Aria Finger, Sayeda Sapieva, Greg Beato, Adam Heiner, Colin Howorth, Willem Crowles, Pim Cronem, Kelsey Capitano, Samiaputa, Anna Pizano, Sarah Tartar, Lear Sermetis, Charlie Manesses, Chinime Ezequena, Emily McManus, and Mina Kursawa. Become a member of Masters of Scale to get access to a year's worth of courses and content on the Masters”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Each of these admirable goals have the potential for transforming our world and saving countless lives, and Stefan is convinced the moonshot platform he helped build up Moderna is a strong enough foundation for doing this. Combined with an active, transparent collaboration across a network encompassing science, government, business, and society, keeping this network open, diverse, and thriving, will open the door to many future moonshots. I'm Reid Hoffman. Thank you for listening.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Stephan did indeed go into fastening detail about each of these and master scale members can hear it all in the uncut version of this interview. But we'll briefly touch upon each before we finish. The first is respiratory disease”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“It was a vindication of the platform that Moderna had been building for a decade, and a clear sign that it would be the platform for many more amazing achievements and the potential for growing a huge network of collaborators. So now you have a platform, obviously. COVID and variance is one kind of applications and variations of it. Does that platform now mean for how you're looking forward at Moderna?”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Openness compounds the rate your network of collaborators scales, and Corey is an expert at leveraging this. Similarly, Stefan had spent a decade creating his global network of scientists, government officials, and business leaders. It had helped him get up to date information on the pandemic and get the funding he needed to deliver the vaccine. Meanwhile, there were promising results from the clinical trials.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“That loose, rapidly convened network of collaborators continues to this day, working under the auspices of the nonprofit US Digital Response.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Stefan's words should remind us that the battle against COVID has been a story of networks of collaborators joining together in a shared essential mission. And this kind of collaboration reaches far beyond the race to create a vaccine. For some more examples, we turn to Kori Zarek, Executive Director at Beck Center for Social Impact and Innovation at Georgetown University. Early in the pandemic, Cori and her team were alarmed at the potential for government systems to be overwhelmed.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Moderna still needed a huge injection of capital to be able to rapidly scale up its ability to manufacture the vaccine, so Stefan decided to raise the money from investors. It would be a time consuming and complex process that would take him away from the important work of actually producing the vaccine. But then a member of Stefan's network, James Gorman, CEO of Morgan Stanley, made him an offer.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Fortunately, when it came to the cost of clinical trials, Moderna and other drug companies racing to make COVID vaccines like Johnson and Johnson and AstraZeneca recovered.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Back with Stefan Boncell, C of Moderna, and if you remember, don't forget you can hear the full uncut version of this interview in the Masters of the Scale app. To become a member, visit masterscale dot com slash membership. Even with the extra space of a two part episode, we couldn't fit in all of Stefan's exciting story, like more details of his tour of Silicon Valley, his insights on how to onboard new staff at speed, and his full vision for the future of mRNA technology. It's all in the uncut interview, and you won't want to miss it. Before the break, we heard how Stefan had convinced his team they needed to pivot and prepare for a global pandemic, but they hit a wall with their suppliers who needed to be paid up front for the huge volumes of equipment Moderna would need to roll out the vaccine.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Stephon had a ready network of suppliers, but none of them were prepared to join him all in on the dismal bet that COVID nineteen was an existential threat. It's worth noting here that not all networks run on the currency of collaboration. Some run on the currency of mutual benefit. Some simply run on money, and that's fine. You can't expect every network to be made of altruistic collaborators driving toward the same mission. But that doesn't mean such networks are bad in any way. You just need to make sure you know the particular currency before you start collaborating.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“This is what all great teams, trying for moonshots, need to do. Don't just accept failure, embrace the failure, get excited by the failure. But here's the important thing to remember. Failure in itself is not something named for, rather aim for the learning that comes with failure. Because what you learn from failure is hard won knowledge, knowledge that more failure versus competitors will not have. That's why you want your team to be a resilient network of collaborators who use failure as a means to zoning in on success.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Gaining energy from things failing is exactly the mindset you have to have coursing through your network of collaborators, and having someone like Stephen Hogue at the center of your network is a good way to make this happen.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“It was exactly the kind of problem that Stefan and Moderna thrived on. For Stefan, this culture is embodied in his friend and colleague, Stephen Hogue.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Moderna's platform was tailor made to respond quickly to a pathogen like coronavirus. As we heard earlier, the mRNA vaccine technology spearheaded by Moderna meant a vaccine could be designed in minutes rather than months. However, putting that vaccine into production so that it would be ready to roll out if the Wuhan outbreak became a pandemic would be a huge upheaval and risk for the company.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Way Stefan got his team on board is not just important for biotech companies moving fast in a pandemic. It's one of the biggest challenges when leading a startup. You will frequently need to make a bet on how a situation is going to develop, and ideally you need everyone on your team to buy in. This is why staying in sync with your team is so important. It makes it easier for everyone to get on the same page, and this greatly increases your odds of success. Stefan made his case, backed up with the information he had collected from his network at Davos and in Washington, and convinced his team that this outbreak needed their undivided attention.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Network of collaborators helped her realize the shocking scale of the outbreak. It also helped to respond with speed and decisiveness against a wider backdrop of indifference and indecision. And this is one of the biggest strengths of a trusted network of collaborators. It can empower you to take the drastic, necessary leaps that others aren't prepared to take. You can hear more from doctor Charity Dean in her episode of Masters of Scale Rapid Response, which you can find in your podcast feed. In Stefan's case, his findings at Davos made him drop all his plans and fly to Washington.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Through that network of physicians, Charity learned when doctors in California started seeing instances of a new pneumonia like illness. She used the information she gathered to map out the possible scale of the pandemic in California, and projected a shocking twenty million cases by May. Charity and her team struggled to make the wider authorities take the outbreak seriously, but then in February, she tapped into a new network known as the Wolverines, a group of seven doctors who had previously worked in the White House. They shared charity's alarm and a sense of intense urgency.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“The disbelief from Stefan's team may seem astonishing, but remember, Stefan was plugged directly into a worldwide network of scientists and experts, and he was getting their information and insights in real time. Another expert who realized the gravity of the situation early on was Dr. Charity Dean, Assistant Director of California's Department of Health. In january twenty twenty, she was already convinced that the outbreak in Wuhan had the makings of a pandemic.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“That's the nineteen eighteen influenza pandemic estimated to have killed as many as fifty million people across the globe, but very few people saw the danger that Stefan, Jeremy, and Richard saw, including Stefan's own team”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“At Davos, Stefan kept tracking the numbers. He also met with part of his network in person, namely Richard Hatchet, CEO of the Coalition for Epidemic Preparedness Innovations, and Sir Jeremy Ferrar, Director of the UK Research Foundation The Welcome Trust. Richard and Sir Jeremy were just as concerned about the outbreak in Wuhan as Stefan was.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Network that Stefan had built up would prove instrumental to Moderna's survival and its pioneering life-saving technology. As we heard Stefan say at the top of this episode, his team was able to design a vaccine in just minutes. However, the full scale of the crisis hadn't emerged. It still seemed then like an isolated outbreak.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“This is Masters of Scale. I'm Reed Hoffman, co-founder of LinkedIn, partner at Greylock, and your host. And I believe you need to prepare to make extraordinary leaps in extraordinary times. And to do this, you need a diverse network of collaborators who share your mission. This is the second episode with Stefan Boncell, CEO of Moderna. In part one, we heard how Stefan cultivated a new risk mindset at Moderna, which enabled the company to build out a platform for launching into action when the world needed it. If you haven't heard it yet, you might want to give it a listen before continuing with this episode. You can find it in the podcast feed. Where we left the story last time, Moderna had made huge strides in developing its mRNA tech and platform, but it had also had a volatile IPO, with its share price dropping amid skepticism about its mRNA based drugs and vaccines, and it hadn't yet released a single product to market.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“A process that would normally take months took Stefan's team less time than it does to update your laptop's operating system, although Stefan insisted on taking a couple more days to quadruple check their design. This blistering speed was only possible because Stefan had spent the past decade honing this revolutionary mRNA technology and the platform for producing vaccines. But it also relied on something else, the formidable network of scientists, business leaders, government officials, and experts that Stefan had cultivated for his entire career, and Stefan would need to lean into this network many more times over the next six months in the rush to save lives. And that's why I believe you need to prepare to make extraordinary leaps in extraordinary times, and to do this you need a diverse network of collaborators who share your mission.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“That's right, 10 minutes to design a vaccine for a totally new viral strain using unproven technology. That sequence, provided by the scientist in China, was like the fingerprint of the new virus. And with it, Boncell and his team could build an mRNA molecule that could help the human immune system identify and kill it.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“In early January 2020, the Chinese scientist published a genetic sequence of the novel coronavirus, now designated COVID-19. Stefan and his team immediately set to work.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Having begun nine clinical trials in the past four years, Moderna was particularly well placed to leap into action against a new virus. By now, Stefan was thinking of little else than the Wuhan virus. And then word came through his network that pathogen had been identified.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Barney was one of the many scientists in Stefan's Planet Spanning Network. And as each awoke to the story, the network lit up with information, speculation, and theories.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Stefan Boncell, CO Moderna, recalling the January morning in 2020 when he first learned of a mysterious illness in Wuhan, China. For most people, the news out of Wuhan got lost in the holiday season wind down, but for Stefan, who had spent the past decade working with some of the world's leading experts in epidemics, it set alarm bells ringing. He immediately tapped into his global network of scientists to get their take. He sent his first email to Barney Graham, a virologist, working with doctor Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases at the time.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
“Folks, Jeff Berman here. I am thrilled to share some of the new names who will be joining us at this year's Masters of Scale Summit. This may be our biggest stage yet. Read Hastings, Meredith Whitaker, Van Jones, Amjad Massad, and more will be there with us october twentieth through twenty second in San Francisco. If you're building something great or you want to build something great, we want you there with us too. Join us at masters of scale.com slash apply 26. That's masters of scale. com slash apply twenty six.”
2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT
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2022-05-31 · Masters of Scale · Extraordinary leaps need solid foundations, part 2, w/Moderna CEO Stéphane Bancel · IDENTIFIED FROM THE TRANSCRIPT