YouSaid · the spoken record
Hamilton Morris
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- 2018-09-20
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- 2018-09-20
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“Which I would not advise people, although strychnine has been used medicinally in the past, and I would actually be curious about trying it at a low dose. But maybe this just shows the sort of person I am.”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT
“A hundred micrograms, all evidence would point to it being less potent than DMT, but why risk it? Start at a hundred, nothing in an hour, move up to two hundred, then move up to four hundred, and then over the course of days very gradually escalate the dose. And if you do it that way, you can say with a pretty high level of certainty that you won't poison yourself because even if it were cyanide, you wouldn't poison yourself if you were doing it that way. You would recognize that it was toxic before you reached anything close to a lethal dose of the material. Same would be true of strychnine. There are very few.”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT
“The potential danger in unknown substances, we shouldn't minimize the potential danger in the known substances because really everything is unknown to a certain extent. And the basic way that he mitigated that risk, and he actually published a scientific article describing his methodology that's worth reading for anyone that wants to get into this area is to Start small to start at one tenth of whatever the absolute smallest imaginable dose might be for something. So if it's a, you know, suppose you made this just completely hypothetical, suppose you made six methyl DMT. six methyl DMT is likely to be inactive. It probably won't have any activity. But just to be safe, if I were hypothetically making that, I might want to start at...”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT
“Right. And that's a great question. There's two ways to think about the risk issue. There's one way that you could say, like, how could he possibly have done this? It was so dangerous. He was the first person to synthesize these things. No one knew anything about them. They hadn't even been given to rodents yet. So how could he possibly take that risk? The flip side is, do we really know anything about any drugs that we take? I mean, there's still fundamental debate going on right now about whether or not cannabis decreases IQ after long-term use. I mean, I have the psychopharmacology textbook that I was using when I was in college says that it does. Then there's endless debate about it. We haven't resolved very basic aspects of the toxicity of the most widely used drugs on Earth. So I would say before we magnify”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT
“It's a really amazing idea. I've been reading it recently. And he was saying physicists are saying the color is made of waves of light or there are these different theories, but what difference does it make? We don't experience color as waves of light. So why don't we take our own experience as seriously as the physicists that are measuring the wavelengths of each color of light? And why don't I sit and describe the experience of green and sit and describe the experience of yellow and what it's like and what does it look like during the day and what does it look like at night and how does it change? Everything, everything that I can observe and to not underestimate my perceptual apparatus is a sort of analytical device”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT
“assays were flawed, but his own experience was the bottom line. That's what mattered. And there have been a number of philosophers that I think had a similar attitude, Goethe also wrote this amazing book on colors. I don't know if you know about this book, but he's, I”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT
“Is certain to be timeless, and that's experience. That's the one thing that never becomes obsolete. And he understood that if he had been, like so many of his colleagues, and said, Oh wow, I just discovered a new derivative of masculine, I can't wait to cut out a strip of a rat's uterus and place it in a bath and see if this masculine derivative causes the strip of uterus to contract. This will be so interesting to find out well all the research that was done on isolated uterus tissue and things like that, it's all obsolete. You can't cite that in a scientific paper and a meaningful way without kind of understanding that it's not considered useful because it doesn't differentiate between the different subtypes of serotonin receptors and there's so many variables to consider. So he understood all that, that these pharmacies”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT
“Well, he would actually often say that he was a terrible chemist because his PhD was not in chemistry. He was more interested in biochemistry and enzymes and things like that. And that's an interest that carries over into a lot of his later work in certain ways. What made him great is not so much the chemistry itself, although that was fantastic. And I would never suggest that it wasn't. What made him great was he had a perspective on science that a lot of people don't have. A lot of people, they think whatever they're doing right now is state of the art because it is. And they don't think, well, what if this fmRI stuff we're doing right now? What if a decade from now it's all garbage? And what if this was a huge, very expensive waste of time? Well, what's the one thing that won't be a waste of time?”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT
“Reinforce my love for him is then following some of these recipes in a university research laboratory and realizing this is real. This really works. These are scientific tools and the synthesis that he provided. Not only effective, they're often brilliant roots to producing these compounds. And what an amazing contribution this man made”
2018-09-20 · The Tim Ferriss Show · #337: Hamilton Morris on Better Living Through Chemistry: Psychedelics, Smart Drugs, and More · IDENTIFIED FROM THE TRANSCRIPT