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Johann Hari

lines on the record: 182
first: 2024-04-29
most recent: 2024-04-29
sittings or episodes: 1
sources: podcast

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“It's really weird, right? In this workplace, you arrive, you show your face to a video screen. It says, Hi, Stephen, you ought fourteen thousand steps yesterday. Your number one hundred and twenty one in the company in terms of steps taken because everyone has to wear like a Fitbit with equivalent to a Fitbit. Everyone uploads pictures of stuff.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“In 2008, obesity very slightly went up in Japan. It was still like laughably low. And they had a real panic and they introduced this new law. It's called the Metabo Law. It's named after metabolic syndrome, which is a really nasty combination of diabetes, obesity, and other problems you can get when you're very overweight. And the law is very simple. Every single company in Japan on a particular day every year has to weigh every single person who works there. And if their weight has gone up, they have to drop a plan with their employer to bring their weight down. And as a company, overall, if your weight goes up, you can be fined by the government. And I was like, how could this possibly work? So I went to a company that does it, Tanita, they all do it, but a company that let me go and see how it works.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Right, and a stroke is one of the worst things that can ever happen to you. Now, it's called reformulation. There's loads of other things we can do like that. We could reformulate loads of foods in ways that aren't even painful to us, right? There's so much we can do, there's so much we can do to be like Japan. I mean, it was a bit weird in Japan, though, because there were things they did that we can't do, right? So I'll give you an example. This was one of the weirdest days of the research for the book.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Thought this whole dilemma never had to happen. This happened because the food industry screwed us over and we didn't regulate them and we didn't stop them. And we can start to do that. And I went to places that have done it. I went to Mexico where they introduced a sugar tax, hugely reduced the amount of sugar that people consume. I went to Minneapolis where they prescribe healthy food for poorer people who can't afford it has a really positive effect. I went to Finland where they had a huge transformation in the food supply. I went to Japan. Here in Britain, there was a really interesting experiment. Bread used to have far more salt in it and a really heroic guy called Professor Graham McGregor, who I interviewed, persuaded the government to just to get the food companies to sort of lure them. I mean, they would have, they threatened regulation, which meant that the companies gave in before they did it, to just massively reduce the amount of salt in bread. No one even noticed, and it reduced strokes every year in Britain by between 6,000 and 9,000.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“I got a couple of bites though. Well, but you don't get. You actually don't even want that particularly, right? And huge numbers of people are seeing that. I mean, Most of the time I have been eating smaller portions of similar shit, but actually even your taste for that tends to kind of wane over time, right? So the last bit's wrong, but I think, yeah, it's one of the things that's funny. I didn't. It's one of the things that made me really angry in Japan. I was thinking All this agonizing I've done, all this worrying, and I worry even more about the fact we're almost certainly about to start a mass wave of drugging children with Ozmpic already begun in the US. I interviewed parents who were drugging their kids because their children are obese”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“I think that last bit, then they're wrong. If you take it, you won't want to eat the KFC and the burgers. And believe me, I have been the king of KFC.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“That A, the drugs don't have a catastrophic side effect, obviously. B, the people who want them get them. And C, it wakes us up. And we go, how did we get to this point? How did we get to the point where we're looking at potentially drugging our children forever, not knowing the long-term effects? Who did this to us and how can we be more like Japan and all the other countries that are making these changes? Now, that's optimistic. That requires a lot of raising of consciousness between now and then, but that's the most optimistic scenario thing. But you're totally right. There could be a scenario. It's probably the most likely scenario if there isn't some big risk that emerges, that we'll just have staggering amounts of the population taking these drugs.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“In the longer term, it won't, and it's not that far off. So in 2032, the patent on Ozempic passes. So then it's not actually that expensive to make these drugs. It's $40 a month to actually make them. It's the rest is profits for nova Nordisk. Who argue, understandably, you know, look, we took all the risks of developing this. We should cash in now. You can see that argument, although I don't think they need to cash in quite as much as they are. So one scenario is it will go out of patent in 2032. By then it looks like the main way of taking some aglatide will be pills anyway. So you can well imagine a situation where you've got $40 a month to take a daily pill that will make you much thinner. I think in that scenario, you're right. Now what I most hope”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“So there's a few assumptions of what you've said. I think you're probably right, but there's a few assumptions. So in a way, what you're saying, there's sort of a few different dystopias that could emerge. One is actually that we don't even get to where you are because it's restricted to a tiny number of rich people, right? So let's start with the first dystopian vision we could have. The first is that we never even get to that point. Let's imagine basically we have a situation at the moment where the real housewives of New Jersey get to be super, super skinny and the real school children of New Jersey get diabetes at the age of 12, right? So we could have a situation where these drugs exist and they work very well, but they are restricted to a tiny elite of rich people, which is kind of where we are.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And I'm thinking, wow, you don't know what's about to hit us all. It was a slightly weird, unreal feeling. I mean, this is for better and for worse, and I think there will definitely be positive effects and there will definitely be negative effects. And I think we can see early on what quite a lot of them are. This will change the lives of all of us in one way or another.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Falfewa knee and hip replacements because overwhelmingly that's driven by obesity, right? So not entirely, but overwhelmingly. So yet if we were talking in 2007 when the day Steve Jobs unveiled the iPhone, I don't think we could have gained out. One tenth of what was about to hit us. And I kept having these moments, traveling all over the world, interviewing these experts. Remember one day. I was in a cafe. I was interviewing one of the key neuroscientists at Cambridge University who was working on this. We were in a cafe and there were loads of people walking past and it's, you know, just random British people, a lot of whom are overweight or obese like I was.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And I felt like that meant I'd done my job because unlike pretty much everything else I've ever written Have ended this feeling as conflicted almost as I was at the start, right? This is a huge thing. It's going to change, and we've talked a lot about the personal dilemmas. It's going to have a huge social effect. Barclays Bank commissioned a very sober-minded analyst named Emily Field to make predictions that could guide investment based on these drugs. And she said, if you want an analogy, you have to think of the invention of the smartphone, right? I mean, this is going to have so many unpredictable effects. Already crispy cream donut stocks have been tanking, the head of Nestlane, Mark Schneider, has said they're worried about their ice cream and confectionery ranges. And Jeffrey's financial did a report for the airlines in the US saying they're going to have to spend much less on jet fuel pretty soon because it takes so much less jet fuel to fly a much thinner population. What I was fascinated by is companies that manufacture hinges for knee and hip replacements are seeing their stocks tank because people are going to need”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Not that there's no cost, but the benefits are really unambiguous and massively outweigh the cost. This is a much more finely judged thing. And it's interesting to me, it's been funny talking to people who've read the book because when we're talking to the marketing teams at both my publishers, because some people who were the first people to read the book apart from my friends, so some of them came up to me and said, oh, yeah, Hannah, I loved your book. It made me really want to take Ozen Pic. Some of you came up to me and said, Johanna, I loved your book. It made me think convinced that you'd have to be completely insane to take Ozenpic. And it was a bit like, you know, the dress, some people saw it as gold, some people saw it as blue.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Yeah, you have to tell them like with these drugs, right? The minute you stop taking them, so within a year of stopping, you regain 70% of the weight you've lost, right? This is one of the big questions around these drugs. Now, that's not 100% of the people regain it, but it's most people seem to regain their weight. So I think there are some times when a drug, a medication, I'm not saying these drugs are that, definitely not, but there are some medications which do seem to be just...”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“We do know there are some medications where, pretty dependably, the benefits outweigh the risk. Think about statins, right? If you have a problem with your cholesterol, what statins do is they block part of your body that makes cholesterol, right? So it's the most commonly prescribed drug in the US. It's pretty close to it in Britain. Almost every doctor would agree. There are some downsides to statins, but sometimes they're just like”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“He personally, I have made the judgment call after looking at all of this evidence that I'd rather take the risk to Mozambique than the risk of ongoing obesity, especially given my family's history and how many men die young of heart attacks. But loads of people will look at the evidence that I present in Magic Pill and take totally the opposite point of view and that they may well turn out to be right and I might well turn out to be wrong, right? I wouldn't debar that there's a fenfen like scenario down the road, right? It's not likely, but you'd be a fool to dismiss it.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Your chances of all sorts of catastrophic complications in your life are really high. It's the biggest single cause of blindness in Britain, preventable cause of blindness. It's a massive cause of leg amputation. More people get an extremity cut off in the US because of diabetes every year than because of being shot, right? I mean, and you go down the list of all the harms associated with obesity. Diabetes isn't even number one, right? Every time I talk about the risks of these drugs, I really worry about the risks of these drugs, right? It's a lot of them. People should go through it very carefully. If you have thyroid cancer in your family, for example, I would strongly recommend you don't take them. If you're already worried about your muscle mass, don't take them. There's a whole range of caveats and clauses. But we have got to be honest about the risk of obesity. And for me, if I'm being honest, I think the choice was ongoing obesity or these drugs.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“A choice between getting diabetes or becoming HIV positive, I would choose HIV every time. If you become HIV positive, as long as you get medical treatment, you live as long as everyone else. If you get diabetes,”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“School of Medicine put it to me, we don't know the long term risks of these drugs. We do know the long-term risks of obesity and they are horrific, really horrific, and much worse than I thought at the start. You know, for example, I'm much quite embarrassed to say this. Diabetes, right? Okay, I knew that you were much more likely to become diabetic if you were obese figures on that are kind of shocking. If you're obese when you're a teenager, your chances of developing diabetes are 70% in your life, right? Shocking. But I thought, all right, diabetics, they get insulin, and then they're basically like the rest of us, right? As long as you've got healthcare, you're fine. Interviewing doctors, they were like, no, no, no. Lots of people think that. If you get diabetes, it knocks on average 15 years off your life. There's a doctor here, Dr. Max Pemberton, a close friend of mine, and a brilliant doctor, who says something to me that seemed really shocking when he first said it. But then he went through the evidence. He said, if you gave me...”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“In the 1950s, doctors started giving people antipsychotics. They were judged to be safe. Lots of people dispute that, but park that for a second. And people took them for many, many decades. And then it was discovered really late in the day that when you get into your 70s and 80s, if you've been taking antipsychotics, you are much more likely to get Alzheimer's disease and other forms of dementia, like much more likely. Now there's no way you could have known that at the start. It was an unknown unknown, right? You couldn't have known that. You had to have people taking it for a really long time before you could find that out. Now, one of the concerns about these drugs is that there will be unknown unknowns that we can't know about. These drugs are working on your brain. They are working very hard on key parts of your brain, parts that relate to memory processing, taste processing, gut motility, right? We don't know, but there's at least some risk there. Now, again, you have to weigh that against the risks of obesity. As Dr. Sean Olivy, who's at Till”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Biggest risk is what he called unknown unknowns. So, you remember that Donald Rumsfeld thing, right? So when he was talking about the invasion of Afghanistan, but when he was the US Secretary of Defense, he said, you know, when it comes to these things, there are things, we're called knowns, there are things we know we know. There are known unknowns. There are things we know we don't know, whereas Osama bin Laden, and there are unknown unknowns, things we don't know we don't know that might hit us out of the blue. And with these drugs, there's a big worry about longer-term unknown unknowns. So for example, we know very little about what happens to pregnant women when they're taking these drugs, right? We know that in the animal studies, when animals, non-human animals are exposed to these drugs, they're much more likely to get birth defects. So one thing Dr. Stanwood said that we should think about, and he stressed this is speculative, we don't know, was think about antipsychotics, right?”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And she died, it happened to lots and lots of people. It led to the largest payout in the history of the pharmaceutical industry up to that point. They had to pay $12 billion to the people whose hearts and lungs were harmed. And that is not that long ago. Now, I want to stress again, that was given to people with a very poor, there was a single study of 120 people of Fen Fen at the point at which it was marketed to people, which is staggering. This has a much bigger body of evidence. So this is not going to be in the short term Fen Fen. But when I looked at the 12 big risks associated with these drugs, some of which have not really been explained to the public, One of the ones that was most disconcerting and was explained to me by a brilliant scientist called Greg Stanwood, who's at Florida State University and is researching these drugs.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And then a group of ordinary doctors in Fargo in North Dakota were like a lot of our patients are getting really ill when they take this and raise a safety signal, turned out the drug company had known about this risk all along. So it was discovered that when you take these drugs, they cause something called primary pulmonary hypertension. It's where the blood vessels in your lungs massively contract and you can't breathe properly. They also damage your heart. I mean, the stories were just horrendous. There was a young woman in Massachusetts called Mary Linen who was about 28 wanted to lose weight for her wedding day, starts taking Fen Fen. A couple of weeks later is trying to climb a hill and just gets really breathless. And it's like so weird here, goes home, it's really breathless, goes to the doctor, he takes her off the drug, but by then she had the problem. She needed oxygen her whole life. She was told she could never have children. And then one day she couldn't breathe.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Popular of them all until these new drugs, which is called fen fem. So this was in the 1990s, early 1990s, a group of scientists decided to combine two diet drugs that had existed until then. One was called flexfloramine. It's an appetite suppressant, but it was never very popular because it makes you very drowsy. So they combined it with phentramine, which is an amphetamine, so it had the kind of, it counteracted the drowsiness, and it had an additional weight loss effect. And it worked incredibly well, people taking it lost as much weight as they lose on Ozempic. And it's actually eerie when you go back and look at the coverage. Front page of Time magazine, the new miracle drug was the headline. You know, by the time you got to the mid-90s, there were 18 million prescriptions for FenFen every year in the US.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“So after the war, they started marketing amphetamines as a weight loss drug, right? And they became hugely popular. They were described as mothers little helper. By the time you get to 1970, 8% of all the prescriptions in the United States were fat amphetamines for weight loss. But it was discovered that when you take amphetamines, you develop tolerance to them. Your body gets used to them. So you need higher and higher doses to get the same effect. But if you take really high doses of amphetamines, you just lose it. I mean, you can become psychotic. It has a really bad effect on you. You don't sleep. It's terrible. So then there was a real rolling back of amphetamines. And then there was some real horror shows like jaw wiring where they would wire up the jaws of obese people so they could they literally couldn't get any food into their mouths but then it was discovered if you vomit while your jaw is wired you can choke to death i mean just like nightmarish horrifying humiliating solutions and then we get to the worst of them all and also the most”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And then they discovered just, I mean, it's almost unbelievably terrible what happened. So loads of the people taking them went blind. And then they went into this horrific fever where their bodies were burning up. So it's an explosive, right? So it was discovered that the way it works is it massively speeds up your metabolism. But when you take a high dose, it gives you cataracts, makes you go blind, and then your body goes into a fatal fever. And the way one person put it is you become cooked from the inside. So they stopped marketing that one. It continued to be used as a pesticide for like years and years because it is so good at killing anything it comes across. So then there was a craze for amphetamines. So again, during the award, during the Second World War, radar people had to watch radars, soldiers who had to watch radars were extremely bored. So they gave them amphetamines to sort of keep them on the job, keep them active mentally alert, and it was discovered they lost loads of weight as well.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“History of diet drugs, Stephen, is absolutely grim beyond belief. So the first kind of modern diet drug was something called dinitrophenol. So there were a load of people in France who were working in ammunitions factories during the First World War. And people noticed that they lost loads of weight, right? Not that they didn't have weight problems at the start, but they lost a huge amount of weight. And it turned out they were ingesting this explosive powder through their skin and breathing it in. So after the war, a load of science.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Yes, it is causing these problems. We know how. It was weird it was like a like I said before, you're seeing this picture form. It was fascinating that there's so much we don't know, which makes it kind of disconcerting. It's like, oh, so this is an experiment on millions of people and I'm one of the guinea pigs. Great, right? So it's disconcerting how much we don't know. But yeah, that is a big worry.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And I spoke to people who'd been through that, and I think that can be a really big issue. There's also with suicidality. So some other people who would say, well, okay, the psychological effects are probably real, but it might come back to what we were saying about dampening the reward system in the brain, right? There were people like Professor Patricia Grigson, who's done some of the really cutting-edge research on effects with addiction in this, who said to me, you know, that's a real concern. Now, she stressed we don't know yet. No one definitively said,”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“So it's usually debated. There isn't even agreement that the drugs cause that effect in a minority of people. You've got to bear in mind at any given time, some of the population becomes suicide or some of them will be taking these drugs. So it's very hard to disentangle that, especially early on. So some scientists would say there isn't even any evidence they cause suicidality. Among the scientists who fear that it may cause suicidality, there's a big debate. Some of it will be you're deprived of comfort food or pleasure. Some of it will be, as Carell LaRoo put it to me, a lot of people who are overweight for a long time say, you know, the reason my life is shit is because I'm overweight. If I finally lose weight, my life will be good. And then they lose weight and they've still got the same asshole husband and they've still got the same job they don't like and they suddenly go into this crisis where they're like, oh, it wasn't the weight that was blocking me. It was everything else, right?”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“For some people, yeah, not for people. Actually, weirdly, I was 33% fat mass when I started, and I went down to 22%, I think it is now. So I lost nothing but fat mass, but I suspect that might be for the slightly humiliating reason that I had no muscle to start with, but I'm not sure.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“The people at that party we were talking about right at the start. None of them were fat at the start, right? People who were already skinny, who were taking it to be super skinny, they're going to see, they're going to have real issues with their muscle mass likely when they're older. So this is a very serious problem. We could be building up a time bomb of more frail older people further down the line.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“There's no way to lose a lot of weight that doesn't involve some muscle mass loss unless you're very, very lucky, right? So obviously, this triggers a huge amount of muscle mass loss. And there's real worries with that, right? If you lose muscle mass, you naturally lose muscle mass from when you're 30 onwards anyway. You lose quite a lot every year. It's incredibly depressing when you look at the figures. You lose muscle mass naturally every year anyway. But if you lose too much muscle mass, you won't, you'll be a bit weaker now, but the real risks are when you're older. So if you have really low muscle mass when you're older, you're at risk of a condition called sarcopenia, which is Greek for poverty of the flesh, basically just means you'll really struggle to climb the stairs, do any kind of physical activity, you're more likely to fall if you do fall, you're more likely to die. It's quite a serious thing. And this, I think, is particularly going to be an issue for people who are already skinny.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“One of the 12 big risks that I write about in the book. So muscle mass loss is a real problem. People who don't know muscle mass is the total amount of soft tissue that you have in your body, and it's essential for doing anything that requires movement and strength, basically. And any form of weight loss causes a reduction in muscle mass. So if you, if someone's very overweight and they lose a huge amount of weight on a diet, they lose a lot of muscle mass. Hopefully you lose more fat mass than muscle mass, but you lose a lot of muscle mass.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And it was striking how much the scientists kept describing it as a game changer, you know, one of them, Tim Spector, who I think you might have had on, described as it's like they found the Holy Grail. They found the thing that causes weight loss, right? Robert Kushner said that to me, who's another one of the scientists been at the heart of it, said we cracked open the treasure chest, we found the thing that controls weight. It's your gut hormones. I worry about the parallels with previous diet drugs, and we can talk about that. These are new drugs working in a new way. And the overwhelming feeling in the sciences, no, this really is different.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Zen Picker Wagovei produces an average of 15% loss of body weight over a year. Munjaro causes a loss of twenty-one percent on average, and the next one that will come down the line is probably going to come out next year, triple G, causes 24.2%. The reason Munjaro works differently. So this only works on GLP1. Munjaro adds another gut hormone, GIP. So it works on two gut hormones, not just one. And GGG works on three gut hormones. And there's going to be more and more drugs. I mean, there's 37 gut hormones that can affect appetite, they think. So there's going to be lots of variants of these drugs with different side effect profiles, different risks, different benefits. So yeah, this is, you know, one of the South African psychiatrist called Correll Larue, who's been at the absolute forefront of the developments in this said to me, you know, when a baby starts to walk, it's been crawling for ages and then it just stands up and it walks. And we are at that point.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“It's the brand. Yeah, exactly. So maglutide, so there's several brands. So there's some aglutide, which is the drug, which has this GLP1 agonist effect. Azempic is the one for diabetes. Wagovi is the one for obesity. They're exactly the same drug. They're made in the same factory. They're identical. It's just that Wagovi is marketed for obesity. And you can in the US, not here yet, prescribe wigovevi for higher doses than you would for diabetics. And then there's other drugs that are coming along the line. So there's Munjaro, which is made by Eli Lilly.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“She said no. Then they said, Are you taking Ozmpic? It's kind of revealing that was the second question they asked. So we know that if you take Ozenpic, there's a study by the University of British Columbia that found it increases your risk of pancreatitis by a factor of nine. So you're nine times more likely to get it. It's still rare. You're very unlikely to get pancreatitis, even when you time is it by nine, it's still a very rare outcome. But, you know, doctors often compare it to the pain of being stabbed. Michelle said to me it was much worse than the pain of childbirth, right? They had to give a fentanyl to take the pain away. So if you get medical care, you recover. But so it's worth people knowing that is a significant risk of just an excruciatingly painful condition.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Pancreatizes a rare side effect, but it's very, very unpleasant. So pancreatitis is basically where your pancreas just goes haywire as a result of taking these drugs. You need to be a woman called Michelle Stesniak, who's in Myrtle Beach in North Carolina. She started taking these drugs, and her doctor said to her, you know, it's a few side effects. One of them is pancreatitis. And she said, no my luck, I'll probably get it. She starts taking it, was really happy with the weight loss. Six weeks later, she went to Pittsburgh to visit her daughter. She woke up in the worst agony she's ever been in. She had this excruciating pain running all from below her breast round her back. She was vomiting, she was shitting herself, she was screaming in pain, and her son-in-law phoned for an ambulance. He thought she was about to die. She was in such a state of distress. She arrived at the hospital, and they discovered something gone really wrong with her pancreas. They said, are you a heavy drinker?”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“I'm not worried about that purely for a selfish reason. So a Zenpic phase is where I'm worried about it for other people. A Zenpic face is where you lose so much weight that your face looks really gaunt and you look kind of hollow and my face is so naturally round. Like babies always smile at me. I think because they think I'm their king. I'm just like a baby that inexplicably got to walk around. I could lose so much weight in my face and not look gaunt that I'm not worried about that myself. There's no health problem with Ozempic face. It's just, you know.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“This then is being further investigated. There are some scientists who dispute it. The European Medicines Agency has not been persuaded by the evidence so far. But that's pretty sobering, right? That's, you know, 1.2% of people get thyroid cancer in their lifetime, 84% of them, I think, survive. A big increase in people getting thyroid cancer. When you're talking about millions of people across the world taking it, is very alarming.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Thyroid cancer. So he's looking okay, is there a difference in thyroid cancer risk in this population? And what he discovered was very sobering. It was published. So the people who taken the drugs had a 50 to 75% increase in their risk of thyroid cancer. Now, when I first said that, I was like, what the fuck? You have to understand what that doesn't mean. That doesn't mean 50 to 75% of people who take the drug get thyroid cancer if it was that outcome, they would pull it immediately and no one would ever take it again. What it means is whatever your thyroid cancer risk was at the start, it will go up by between 50 to 75% if this research is correct, right?”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“There was some catastrophic effect, we would know it would have emerged in diabetics, right? Now he would also add, well, it could affect obese people a bit differently than diabetics, so there's some gaps in the knowledge. But he said, look, this drug has been used by enormous numbers of people all over the world without some huge safety concern emerging. But others have said, okay, let's really dig into those diabetics then. So that's what Professor Faye did. So they've got very good health databases in France, the best in the world. So he decided to look at diabetics who'd taken these drugs for three years sometime between 2006 and I think 2015. So he looks at loads of the diabetics who've taken them and then he compared them to a group of other diabetics who were very similar in every other way but had not taken these drugs to see how their differences in outcome. And he was particularly looking for one outcome. We know that when you give these drugs to rats, they are much more likely to”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Well, there's a huge array of risks, some of which are very, very serious. So I'll give you a few examples. I go through lots in the book. There's a professor in France called Professor Jean-Luc Faille, who works at the University Hospital in Montpellier, who was commissioned by the French Medicines Agency to investigate these drugs in the safety around these drugs. And one of the reasons lots of people have felt very happy about the safety of these drugs, and it's a good reason, is they in their rollout for obesity, is people have said, like Daniel Drucker, for example, who I mentioned, who discovered GLP1, they say quite rightly, well, look, diabetics have been taking these drugs for 18 years now.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“If there are Americans and the polling is right, forty seven percent of Americans have said they would be willing to take these drugs actively wanting to take. Oh, they want to take.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And the Julius is a kind of incredible. If you look at the effects on diabetics, obvious. But if you look at the health effects that are emerging around these drugs, and this is very close to my heart, literally because of the heart problems in my family, if you take these drugs, if you started with a BMI higher than 27 and you take these drugs over the next five years, you are 20% less likely to have a heart attack or stroke. So we're talking about, this isn't some people are like, oh, this is vanity, and there's an element of vanity in me and in most people taking these drugs, I'm sure. But this is having massive health benefits for lots of people.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“And he discovered that if you combine it with insulin, it produces more insulin. So that's why it's so valuable for diabetics. And immediately he was like, whoa, that's really significant. So then other people in the lab, Professor Svetlana Mosjoy, gave it to rats, put it in rats, and discovered it, in fact, produced insulin in rats. A team in Copenhagen put it into the pancreas of pigs, discovered it produced insulin there. And that set in train what later became giving it to diabetics. So that's the most obviously greatest benefit of these drugs that was initially discovered is they hugely help diabetics. Then the effects around appetite were discovered separately initially here in London in the Hammersmith Hospital. That was when they discovered, oh, if you inject people with GLP1, this is before they had copies of it. If you inject people with GLP1, it reduces their appetite. Oh, okay. You can see where their thinking went from there. So there's dual uses.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“Have a dual effect. So GRP1, the hormone GLP1, and this kind of replica of it stimulates the creation of insulin, which is obviously what diabetics are lacking, either type 1 or type 2 diabetics. So the whole thing was discovered by accident. I interviewed the guy who discovered it, a guy called Daniel Drucker, Amazing Man. So they discovered, he was just looking at, so your whole body is made out of cells, right? And in the 70s, it was discovered there were new ways of looking inside cells that human beings had never had before. So by the 80s, 1984 was when he made a breakthrough. They were just going through different cells in the human body trying to figure out what they do. And they got to the glucagon gene, which exists inside your pancreas. And they were trying to figure out the glucose.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“You were turned down by a doctor on Zoom, you can just order effectively counterfeit ones online very, very easily. So I'm extremely worried. I think we're going to have a, there are many downsides to these drugs, possibly the worst from my point of view, one of the two or three worst is you're going to have a huge wave of young women who get hold of these drugs and do a lot of harm to themselves. Now, there is something we can immediately do to massively limit that harm. Lots of the eating disorders experts I interviewed like Dr. Kimberly Dennis is one of the leading experts in the US, said to me, these drugs should only be given by prescription if you go to a physical doctor and the doctor you physically go to to get them needs to be trained in detecting eating disorders and referring people for help with eating disorders if that's what they think they've got.”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT
“So, this is part of the problem, and this leads to one of the really big risks associated with the drugs, which is eating disorders. I am really, really worried about this. So there are lots of young girls in particular, some boys, but it's mostly girls who want to starve themselves, right? We know that. It hugely rose during the pandemic. And this is the most effective tool for self-starvation human beings have ever come up with. So I interviewed a lot of eating disorders experts who are terrified about what's coming down the line. And the truth is it is very easy to get hold of it. You could go online now. You clearly do not meet the criteria for getting these drugs, right? You've got to have a BMI of higher than 27, which is a BMI that comes from fat mass, not muscle mass. So you would not meet the criteria at all. If you went online, you could go and see a doctor on Zoom, lie about your BMI, and you would get it in the mail two days later, right? They're meant to check your BMI, but on Zoom, that's very hard to do. If in the unlikely...”
2024-04-29 · The Diary of a CEO · Ozempic Expert: Ozempic Increases This Disease By A Factor Of 9! They're Lying To You About Ozempic Side Effects & What It's Doing To Our Brains! - Johann Hari · IDENTIFIED FROM THE TRANSCRIPT