YouSaid · the spoken record

John Crowley

lines on the record
145
first
2017-02-28
most recent
2017-02-28
sittings or episodes
1
sources
podcast

Every line below is reproduced as it was said and linked to the record it came from. Nothing here is summarised or generated. Directory · Search · Corrections

  1. “Megan loves high heeled shoes even though she's never walked a day in her life, and that says something about her. Thank you, Tim. This is awesome.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  2. “So, take a look at it. She's a remarkable young lady, and to gain some of the insights from Megan, I find valuable and am just blessed to be able to share with others.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  3. “I think in the scope of healthcare, because it's the one thing we all deal with, always realize that you have got to be your greatest advocate. No matter how awesome your doctor is, how wonderful your healthcare system is, nobody's going to wake up thinking, how can I make this person better, healthier, safer, happier, whatever it may be. So that importance of being your own patient advocate is just so critical. And one thing I would ask, my daughter Megan asked for this. She's just such a remarkable kid as my boys are too, but Megan is just a really special person. I've learned an awful lot from her. Many people have been touched, just a special human being. And I've asked if she'd share more of her life perspectives with people because she lives, you know, most people would look at Megan and think, God, this poor little kid, this, you know, this pity on this young lady, and she doesn't feel that way. She feels so blessed.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  4. “I think it's the, you know, I always ask my kids, I said them, are you happy? Are you safe? Are you fulfilled? So to me, it's maybe a combination of all of that happy, safe, fulfilled.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  5. “I always start with the Hail Mary. So for me, it's the Hail Mary and the Our Father. So having grown up in a Catholic family in many Catholic schools, that's my prayer, my peace time. As I've gotten older, though, I've stopped. Praying for things. I don't mean material things, never that, but help me with this, help me with that, intervene. Sometimes, yes, pray for others, yes. What I really try to pray for is what I guess I'd call Tim kind of. Peace, grace, strength, and thanks. And to me, that's always a nice way to try to fall asleep.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  6. “I try to stop the email by 9 p.m. And sometimes you can't, but try to stop it by 9 p.m. Now, we do, you know, we've got operations in Asia as well, so Asia, United States, Europe, there really is no downtime anymore. But I try to stop it. And then I try not to use electronics after no TV, no iPad, no iPhone, try to read. For me, reading helps. And then as I said, I don't meditate, but I pray.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  7. “So we try to eat healthy when we stay home. You know, the chicken fish, steaks, Eileen's been trying some of these prepared meals, the plated, the Blu apron. Sure. Those are quite good. But I love pasta. You know, my grandma was from Sicily. I love pasta. So I try to limit it, but probably one or two nights a week we'll have a big pasta dinner, always on Sundays if we can with family. Kind of a effective growing up in a big half Italian family. And the Irish side that loved the pasta too.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  8. “No, no, no, they're either either or. Either or. Yeah, no, that would actually sound like it would be kind of gross. What do you do at the cross?”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  9. “Peanut butter, I'm sorry, almond butter and bananas in the morning if I can. I'll take a frozen egg white and throw it in.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  10. “So then a little bit of dinner, time with the family, wrap up a little email. And the last thing I do before I go to bed every night, I pray.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  11. “Increasingly into potential. I find as I get older my strength is about the same as when I was young, my endurance is about the same, a much slower and I get hurt way, way more easily.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  12. “If I've got limited time, 30 minutes, pushups, pull ups, sit-ups, and dips. Lots of push-ups, pull up, sit-ups, and dips, because you can fly through them. Great workout, and it's hard to get hurt. If I've got more time, I'll build in, you know, some of the bench press, some of the shoulder press. I'll do kettlebell swings, those types of activities. Try to mimic a CrossFit workout. And if I can find the time at least three days a week, I try to get out to CrossFit when I'm not hurting myself as CrossFit.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  13. “Post lunch. Post lunch, one two o'clock. It'll have to vary by certain other commitments. But it's always on there. And I do try to take it as a time to step back into think, where are we? What have I learned halfway through my day? What do I need to complete by the end of the day? And what happened unexpectedly that I have to pivot around? What I also find, though, is about 50% of the time there is such demands on my time that I've got to use it for something else. John, you got to get on the call with this clinical site or John these investors need to talk to you. Do you have time? And that's okay because, you know, rather than everyday pivoting things around, at least I know I've always got a little bit of flexibility built in. So if the kids are home, I try to get home at a decent hour, spend time with them. I get a more intense workout in when I go home, either go to CrossFit or do something in our basement, try to do more of a...”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  14. “Cap and 300 employees who invariably there's the details and what I'll call the grind of the business that you've got to get through and there's the invariable demands on your time. I do try, and I don't succeed more than 50% of the time, but I try and it's on my calendar every day, one hour of thinking time.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  15. “I'll try to leave the house around 7.15 or so. So try to beat the school traffic of all the schools in Princeton. I'll do that. Get in the office. Try to have a bout an hour of downtime. I try to not run the company by email. I think it's too easy to get in and say, okay, what email's hit since I got off my elliptical? Let me respond to those. I try really hard to limit the email time set a block in the morning on the elliptical a little bit more when I get in the office and then spend the time with the team, the people. We try really hard in our company with that patient-centric view to bring patients in living with the disease. If you come to our company, you'll see we've got portraits and pictures and paintings of all people living with rare diseases and their stories around. And we try to bring them in and just be absorbed in that. Now, we're also a public company with a billion dollar market.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  16. “I use my iPad, prop it up, and just flip through, you know, download the Wall Street Journal, look at the journal, look at the New York Times, flip through emails, get through that, and then get ready and head off to work”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  17. “So I try to get up early, usually not early enough. I'll try to get up by six o'clock in the morning. And with that, I've always got to plan things I'm going to do. Maybe I'll try to exercise or do that. I don't always have a set plan every morning. What I find inevitably is that I'm rushing out the door, whether I get up at 5, 6, or 7 o'clock. So it's a little bit different now too with the kids, John and Megan in college and Patrick a senior in high school. I've got a little bit more time in the morning. It used to be just a flurry of activity, getting kids ready, nurses coming and going. In between it all, we decided it would be great to get two Jack Russell puppies because we didn't have enough activity in the house. I'd say a typical day, though, for me, Tim, is, you know, wake up at 6, shower, get ready, catch up maybe 30 minutes on the elliptical, read the headlines of the news, what happened the night before. I've got now seven offices in Europe, so catch up on the emails.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  18. “We getting to this concept of a singularity of combination, man and machine becoming as one obviously many books and some movies written about this. And it can be scary. But to me, it's actually unbelievably exciting. You know, if we can do it for the right reasons in the right way to extend and enhance human life, I mean, that's what it's all about kind of gets us back to time. time and quality of life. And that's pretty darned exciting.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  19. “In fact, and do so in a way that you've now permanently changed the human germline so that that genetic change is inheritable to their children. Obviously profound ethical consequences, but I really believe that if we keep pursuing these technologies, some of which are already, many of which are already in clinical development, 10, 20 years from now, we can alleviate an enormous amount of human suffering. Now, can we unlock the secrets of aging? Is the aging process itself a disease? In many ways, it really is more what happens in aging is more and more of these little mistakes in our DNA happen. And over time, they accumulate, and over time they lead to cellular inefficiencies, they lead to a lot of misfolded proteins in our body. What if we were able to change that course and do”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  20. “Why are we programmed to die now at 80 when we were programmed to die at 47 a century ago? We're not. We intervened. When what we've effectively done is begun to change the slope of human evolution. So we now have tools that not only can we provide drugs that can cure an infection or drugs that might prevent or treat heart disease or rare diseases or cancers. We're now to the point where you look at the gene therapies that are being developed. You look at a new technology of gene editing actually being able to go in and manipulate human, the human genome in an individual and fundamentally change their health course.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  21. “I really think, Tim, that we are on the cusp of a golden age of medicine. So we've come a long way. In the last century, we've almost doubled the life expectancy here in the United States. And we did that with better hygiene, better nutrition. But the greatest single contributor to that contributor to expanded life expectancy is medicines, medicines that are extending and enhancing life. So we've come a long way. The average life expectancy is almost 80 years now.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  22. “Develop treatments that will help people with all of those rare diseases. And in the meantime, my big vision for the company is I want to be at the forefront of human genetic medicine, which I believe in the years ahead means that we're going to be at the forefront of human health. That's pretty exciting.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  23. “The rare diseases, you know, what's so rewarding about working here is that not only are you working devastating diseases where, yes, you can save people's lives, you can potentially even one day cure them, that in itself is meaningful. Beyond that, I really believe that by understanding human genetic medicine, understanding what's causing these diseases and how they may be treated, we're going to unlock the secrets to treat much more prevalent disorders. You look at a disease like a Parkinson's and Alzheimer's, many of the cancers. They're really just human genetic diseases that we don't completely yet understand. So one person with one, you know, think about it when we started out, we wanted to help our two children with a lot of people's help. We were able to affect everybody living with Pompeii disease. Now at Amicus, we're working on multiple rare diseases. Hopefully we'll be able to...”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  24. “Made the news as well. About a month or two later his mom Linda got together to thank those police officers who made it happen. They started to think about God, He didn't live long and how tragic it was, but boy, he sure loved that day and that experience. And they were so happy and they realized it made their lives better. The people who gave him that gift, that wish. And then they said, well, why stop? Maybe we can do this for other kids. And that's how the Make-A-Wish Foundation came to be because a couple of people just wanted to help one sick little boy. Now fast forward 36, 37 years make a wish foundation has granted over a quarter of a million wishes to children that have fundamentally changed their lives, brought joy to people with life-threatening illnesses, and the communities that's affected. So you can do a lot of good by touching one life.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  25. “Chris had advanced leukemia. It was in Phoenix, Arizona receiving some treatments. Chris was going to die. And some nurses, family members, and then police officers heard about it, that Chris always wanted to be a cop when he grew up. So these cops heard about it. They said, well, let's help this kid be a cop. They actually made him a little uniform and got the doctor's permission to take him out of the hospital for the day. And they made him a cop. They deputized him with a judge, put the uniform on him. They took him up in the police helicopter. I mean, just a true copics police officer experience. And he went back to the hospital after that day. He was on the local news in Phoenix. It was great. Two days later, Chris Gracious died. He was actually flown back to Illinois, where his family was from, was given a police officer funeral.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  26. “Look, I'm a big believer in going deep. Don't go wide. Have the impact, even if it's on a single individual. Because think about the ripple effects of meaningfully changing somebody's life, even one individual, Tim. So you mentioned the Make-A-Wish Foundation. It's such a great example. So Makeawish back in 1980 was a little boy named Chris Gracious, a seven-year-old.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  27. “So, you know, again, so you take these 7,000 rare desserts. I mean, the essence of your question is why rare diseases and why not put the money into much more.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  28. “Oh, yes, always all day long. And she said to me, she said, Are you going to be here in the morning? I said, Yeah, I'll be here. She said, Would you take me to school? I said, Yes, honey, I'll take you to school. And she said, Good night. I love you. I said, good night. I love you. And I walked out, and I realized in that moment, Tim, the humility that has to come with any degree of success. Success is pretty fleeting, of course. And I realized Megan absolutely, truly did not care that we'd raised a bunch of money, that I was on TV, that we flew around in a private plane. What she cared about was that her dad was gone for two weeks on a really long business trip. That she missed him and that he was home. Was going to take her to school. And I think in that moment, I realized, you know what, that's why we're doing this for those moments.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  29. “She looks at me and she goes, But Daddy had this yellow power tie-on. She goes, But daddy, that tie looks really good on TV on camera. So I'm like, okay, thanks, Megs. And then she said to me, though. She says”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  30. “She said, Daddy, I said, Megan, she threw her arms open, give me a hug. I gave her a hug. And she said, I missed you. I said, Megan, I missed you too. She said, Daddy, how was your big business trip? I said, well, and I had my suit on and all of that standing above her. And I said, well, Megan, I said, the trip was good. You'd be pretty proud of the old man. And she said, I know, Daddy, I saw you on TV today. I said, well, really? I said, so how'd I look? And she said, Well, Daddy, you looked really, really. Now I'm thinking, I don't know, powerful. She said, Daddy, you looked really, really kind of short. I'm standing there now. There's this awkward silence. Now, Megan is also the master at How did Dan with faint praise?”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  31. “So I went in. The boys sleep pretty soundly. So John and Patrick were sleeping, gave them a kiss they didn't stir. I went into my daughter Megan's room. She was ten years old at the time. You know, still hooked up to a ventilator, laying in bed, sleeping quietly. She's a pretty light sleeper, so I gave her a kiss, and her eyes opened up.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  32. “So you go through, we had a great IPO eight times over subscribed. Wall Street on now this second company, Amicus, gave us a $300 million pre-money valuation. We raised $75 million. We go to New York. We close the deal. Lots of back slapping at the board level. The next morning we're there. We close the stock exchange. I'm on CNBC. We're being interviewed. For an entrepreneur, that's about the height of success. You feel pretty darn good about yourself. People couldn't six years, seven years before that. I was knocking on doors trying to raise money just a little bit to pay the rent for our company. Now people were begging me to take tens of millions of dollars. I had the company in. We did a big celebration, a party, but I was pretty tired of his two weeks on the road, pretty grueling. You go in check on the kids.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  33. “But I still felt badly for the kids. I felt badly for myself that I was going to miss that time. That was a conscious decision we made, and it was a bet that paid off for us. But I still struggle with that, Tim, finding the right balance. When we share a brief story with you, when we went public, amicus went public in May of 2007. We'd only been around for a couple of years. It was an IPO with a lot of fanfare that people were throwing money at us. You know, you go out in these investment banks, you do this roadshow. Sounds pretty sexy. It's grueling. It's like, you know, groundhogs day, 80 of the same meetings around the world. Now, the cool thing is, you know, the banks will get you a Gulf Stream five or whatever to fly around in. I'd never been in a private plane, although it was pretty cool.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  34. “It is the one thing that I struggle with most. It is finding that balance in life. And many times in life I've gotten it wrong. And I probably still don't do it very well. So look, you've got to work hard. Hard work is the price of success. But you've got to find those times to step back. And even if it can't be the quantity of time that you want with friends, with family, treasure the moments that you have. For me, the toughest decision years ago in starting that first biotech at Novazyme was realizing that I was going to be, or every Monday morning flying to Oklahoma City and flying around the world. And that my kids may live a very short time, and I was going to miss most all of it. But Eileen and I, she said, look, you go out and search for the cure, I'll take care of the kids. So we had a great division of labor, and”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  35. “But I have to share this with you. You're going to die. Now somebody, they turned white. Oh my God. Yes, and I'm virtually certain. I can't predict exactly when. But on average, if you want time, you want to know, I think you've got 49 years left. That's it. You're going to live to be 80, right? 79.9, I think, now is the average life expectancy. So we're all going to pass away from this earth. So what do you leave? And what did you do in the meantime? But also, what are you fighting for? And you're fighting for time. And what do you do at that time?”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  36. “It happened every day to people. That could happen. So, what do you do? You forget about work, you focus on family, love, all of a sudden life becomes very sharply in focus. If you went to that doctor and he said, Look, you've got some illness, you've only got five years to live, still very serious. Life comes pretty sharply in focus. You may not walk away from your job that day, but take some time. Maybe start to think about therapies. What if you went to the dock and you're 30 years old and had your physical and the dock goes through everything, blood work, everything looks great. You're following the Tim Ferris regimen. Your great physical shape.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  37. “Life is a fatal illness. And I think of, you know, I think about that. What if? You went to the doctor tomorrow, God forbid. And he said, I've got your test results back, and you're only going to live six more months.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  38. “She wrote something to him. She wrote that at the end of the day, we're all just searching for time, time with the people we love. And we treasure it, we hold on to it, and we hope and pray for another, even as we continue into the unknown and the unknowable that we all call life. And that's it. To me, it's all about time. What did we do with our medicine? Why did we do that? We did it to buy time. Time and life. And so far, Megan and Patrick now have lived 13 years longer than they otherwise would have. Now it's given them time, given us time together. It's given them better quality of life and quality of life, of course, is so important. But again, it's given me as an entrepreneur and our scientists time to come up with maybe the next best medicine and new technologies so that cycle of innovation, that virtuous circle of healing that can happen with great medicines.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  39. “And the thing that makes it better is to realize take that step back and think about What matters in life? To me, it comes down to time. In Gita's book, The Cure about our family in the epilogue to that book after having spent two years writing it and spending a lot of time with her family and researchers, a lot of time with our kids.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  40. “What I've come to realize is there is no way to substitute pure experience. Now, we will all go through adversity in life. So you don't have to worry about, oh my God, I'm never going to get the experience of adversity. Believe me, you will, sometimes more than you ever, ever thought you would.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  41. “Look, the old adage is trial adversity builds character. And I think that is true for most people. The trouble is it's very hard to create artificial adversity. Now we can do it, and you certainly in your books and your lectures, you talk about different ways that you've tried to do it, that you've taught others to do it. You could do it through rigorous physical training. You could do it through a discipline. You can do it through, you know, focused more on certain activities in life that require sacrifice. And that's all true. And I think that's all an element of it.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  42. “Asked him, though, after years of effort in a big experiment that failed, what did you do? And he said, Thought about it. I thought about how I'm going to tell my family, my co workers, the people put the money into this that it didn't work. So I walked. I went to a park, he said, and I thought about what I was going to say. And I read it in this article, Tim. He said, and I looked out in the park and I saw dozens of children at play. And I realized without a vaccine, many of them would develop polio, would suffer, and may die. And he said at that moment, I realized the enormity of my work, and I went back to it with a renewed vigor. And I've always tried to think about that. What if SOC didn't go back to try it again? And I've had plenty of failures in biotech, plenty of drugs that haven't worked, studies that were delayed, every setback you could imagine. And I try to think about that.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  43. “So polio was the scourge of the society from a healthcare standpoint in the 40s, 50s, obviously FDR affected by it. A young researcher at the University of Pittsburgh Medical Center named Jonah Sauk had an idea that he could develop a vaccine for it, got some funding for the infantile paralysis foundation, what we now call the March of Dimes. Developing a vaccine worked on it tirelessly his whole lab, well-funded, put it together, tested it, I mean tested it on himself, on his co-workers, his family A large series of experiments, and it didn't work. And there was a great interview years later that I've read. It was a magazine ironically called Wisdom. And they talked to Dr. Sock about that. Because, of course, he then went on to invent the vaccine that saved countless lives and effectively eradicated polio from the world.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  44. “You know, you look like people, you know, outside of our industry and probably most in biotech, I've never heard of Bob Swanson and her Boyer. Swanson ended up dying in the 90s of a brain tumor. But, you know, the vision that they had, the risk-taking, those are real heroes. Another one is you go back to probably the earliest biotech entrepreneur who never even knew he was an entrepreneur is Jonah Sauk.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  45. “Boyer had to leave the academic world, but they did that. And think, you know, what would the world look like? What would our industry at least look like? Biotech without Genentech. It would be very different.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  46. “A young venture capitalist at Kleiner Perkins. Bob Swanson, he was looking at ideas, came across some papers written by University of California at San Francisco, UCSF professor named Herb Boyer. And the papers talked about protein engineering and DNA sequencing and expression of proteins in animal-based cells and maybe someday making medicines out of this. So Swanson took a drive up, knocked on his door, started asking questions, started putting stuff on a board, literally went across the street to a bar, started putting it together on a cocktail napkin. And think about it. So you talk about in building business, the importance of vision and risk-taking, all of that. But think of what those guys did. Not only did they have to take a chance on a technology with all those challenges, they had to start a company. Okay, they had to start an industry that didn't even yet exist. Sell it to the partners at Kleiner.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  47. “We talked about the importance of persistence and resilience. You can go back to the founding of the biotech industry only goes back 41 years, 1976. Isn't that crazy? And it was founded here in San Francisco in the Bay Area.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  48. “And he picks a villain, and it's Benedict Arnold. Now he tells the whole story in very rich detail about the American Revolution, very character-centric. And you got to realize what they did, you know, and it's told in that book is just so extraordinary and has never happened before or since in the history of the world of people coming together for that cause. Within the American Revolution, realizing they fought for this great ideal, lots of sacrifice, they mutually pledged their lives, their fortune, their sacred honor. Every single person who signed the Declaration of Independence died peacefully in their own bed. Where else has that happened in the history of the world? So, great lessons in life. I think it's a great book. It's a great way to learn history.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  49. “I'm a big fan of history, Tim. American history, revolutionary history, living now for almost 20 years in Princeton, surrounded by revolutionary history. Even as a kid, I was. So there's a great book by an author named Benson Bobbrick called Angel in the Whirlwind. And it's a history of the American Revolution, obviously countless histories of the American Revolution have been written. This one's pretty special in that great storyteller. There is a great hero in the book. You want to guess who the hero of the American Revolution is? It's not a trick question.”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT

  50. “And things will invariably go wrong in the fog of war if and when they go wrong, what are my options? And what's the optimal path through that?”

    2017-02-28 · The Tim Ferriss Show · #225: John Crowley -- The Real-Life Captain America and Bruce Banner (Seriously) · IDENTIFIED FROM THE TRANSCRIPT