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Paul Stamets

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2018-10-11

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2018-10-11

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1. “Enrolled in the clinical study in order to have a statistical significance almost uttered there. So that's what we're looking at is looking at stacking this and maybe do this clinical study in Canada. Right now the FDA is very favorable to these clinical studies. I had a report from somebody met with the FDA regulators and their scientists and they said they have never seen a drug that was so non-toxic, so effective from one treatment in the history of their looking at approving new drugs. And they were like, so the FDA scientists are quite focused on this. It's something we all, the difference between a medicine and a toxin is dose. I wouldn't call it psilocybin a toxin.”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

2. “Socially and intellectually. I know a lot of people were interested in that. And plus it's kind of groovy. It's kind of sexy. These older people say they're kids. Yeah, I'm microdosing. Microdosing is extremely popular”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

3. “Oftentimes occur from the deadening of the nerves at the fingertips and the toes. It struck me that if I could excite the nerve endings, perhaps I could drive these lions mane and the psilocybin to the end points of the nerve systems if the vascular system is still intact to deliver these compounds to create neurogenesis and prevent neuropathy at the end points of the nervous system. So I filed a patent stacking niacin, psilsibin, and lion's mane. The psilsibin dosage is about 1 20th of a gram. Now that is below the threshold of what people would experience any change in consciousness. So I know lots of people who would not dare take a sulcibe mushroom. But the idea of taking 120th below threshold dose that would create neurogenesis and perhaps make them cognitively more astute and make them a better person.”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

4. “Prior art speaks against conventional wisdom. And when I gave a talk at MAPS recently, I asked the audience about 800 people, how many people remember during the 1970s and 80s, it was well known, especially on the West Coast, that if you want to come down from a bad trip on Sulcibin or LSD, you could take a bunch of niacin. You get a hot flush, and people don't know when you take like 500 milligrams of niacin, you get red and you get tingly all over your skin. You have this niacin flush. And about 50 people raise their hands. I actually recorded that. I needed that for my patentability because that was common knowledge that niacin counteracted the effects of sulcybin. I think not. Number one, there's no evidence that that's true, but it was common knowledge. Number two, because it excites the nerve endings neuropathy.”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

5. “Is a very timely question because in two hours from now, I have a group of financial people that are key in supporting the current psilocybin research, John Topkins and elsewhere. They're arriving here specifically and saying with me for three days to talk about exactly this. I had an idea, and I'm going to probably open source this. Sometimes I file patents. I call them blocking patents. I file a patent that I think should be open source in order so other people can't get a patent on it. And this might be in that category. This whole patent landscape, I see both sides of the arguments of open sourcing and then also keeping things closed source. You can look it up. Stacking lions main psulocybin and niacin, nicotinic acid. Now I spoke before what is patentable.”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

6. “Of the tissue, they could see that the amyloid plaque had largely resolved remyelination had occurred. And so you bundle that with, you know, you've got a behavior as well as physical evidence of regeneration of myelin. So lion's main mushrooms are just a very, very fascinating mushroom. Think about Einstein in his last days. I think about some of my mentors in mycology and their very last days. We are losing encyclopedic knowledge. These are mental giants. that have so much to give to the next generation as part of our national heritage, our intellectual heritage, and to lose these geniuses with all this experience, all this knowledge, all this sense of being and context, to lose them at the end of their life is us losing a library that just library books that fall into pieces in your hands. And I think it's so important for”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

7. “Plaque formation is a very, very potent toxin neurotoxic. But mimics that of what happens in the nervous system, Alzheimer's patients, because amyloid pack formation can be conform, their behavior changes, they lose the ability of navigating through mazes, they lose the novelty, acquisitiveness factor. The short-term memory is basically erased or much of it. And then they fed them lions mane mushrooms and they dissected the mice, and sure enough, they saw that the amyloid formation was there. And then those fully diseased mice, when they would then feed them lions main mushrooms for 23 days, they regained the ability of navigating through maize. They re-engaged inquisitiveness. It's called the novelty response, the novelty experiment. And then upon dissecting those knives in the resections,”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

8. “Much more neuroregenerative. There's been several clinical studies that have come out on mild cognitive dysfunction out of Is doing microdosing of psilocybin stacked with lion's mane. is a big subject of research. You go to PubMed or Google Scholar Alerts, put in Lion's Maine and neuroregeneration or NGF factors. And there's several dozen peer-reviewed articles extensively exploring the regeneration of myelin, which is the conductive sheath on the axons of nerves. Those who get Alzheimer's, for instance, have amyloid plaque formation that interrupts and erodes the myelin sheath, prevents neurotransmission. And so lion's mane mushrooms have been demonstrated behaviorally in people with cognitive tests, but also through dissection of mice prior to using lion's mane, they would inject these mice with a polypeptide that induces amyloid.”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

9. “So, the Arenacians are some of the strongest nerd growth factors ever discovered by science, NGF factors, or called nerve factors, and they regenerate myelin on the axons of nerves. So now Lion's main is perfectly legal. It has a long history of use, multi-thousands history of use. It looked like palm-poms that cheerleaders use. It's a white cascading crystals descending teeth. And it's a beautifully beautiful mushroom. It tastes like shrimp or lobster when you add butter to it, when you cook it. But the compounds that are most neurogenerative are from the mycelium, not from the mushrooms. And so the Arenaceines are from the mycelium hericinones are another group of neurofactors. They're from the mushrooms. But the Erencines by far...”

   2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

10. “Learning for being able to articulate responses and new challenges in the environment. The mushroom fruit body is at the end of a thing, but people Attracted the mushrooms and they fear that typically nature which is ephemeral. Now we're around trees and we're around dogs and animals and plants for weeks, months, years. So the familiarity factor of constant exposure day to day gives us some confidence in, oh, that animal's not going to attack me or that plant is one that my answers have been using and we understand it. But mushrooms that come up and disappear in four or five days. Some can feed you, some can kill you, some can heal you, some can send you on a psychoactive journey, that which is so powerful but so ephemeral is naturally to be afraid of them. So we have about 200 species of mushrooms that are edible, medicinal. I don't know the difference between edible and medicinal anymore. All edible mushrooms have medicinal properties. But the mycelium expresses a lot more of these compounds. And with lion's mane,”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

11. “But the mycelium is articulating constantly a bio shield of defense from exposure. When the mushrooms form, good luck to any bacterium that's going to rot it. It's going to spoliate in four or five days and then gives themself up anyhow. Moreover, I think that the sequence of bacteria that rots mushrooms is absolutely instrumentally important for the evolution of the ecosystem to give rise to the trees that create the debris fields that feed the mycelium. So these are deterministic microbiomes. And the microbiome, the fungal biome, is determining the microbiome because many of the bacteria are adversarial. Some of them are commensal. Some are actually mutualistically beneficial. So the mycellium is this articulation of this network that because of epigenesis, the ability to respond to environmental stimuli and upregulate and express new gene expressions, it is a fertile ground for”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

12. “Mushrooms are what people know, but mycellium is emerging as a tremendously important reservoir of many bioactive molecules that supersede the benefit of mushrooms. Whole genome sequencing of Rishi mushrooms in the genus ganoderma, the commonaki, the 10,000-year mushroom, the mushroom of immortality. These are all common names out of Asia. The 25% more genes are active and expressed in the mycellial form than it is in the fruit body form. The fruit body is a mushroom form. That's the end of its life cycle. So much of our research has found going side by side comparisons of mushrooms, which are protein-rich. They're beta-glucan rich. They have lots of carbohydrates and polysaccharides. They're nutritionally dense.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

13. “You've got the repellency property, right? The psulmon repellency property. Like, I'm not touching those for months, but boy, that was a great experience. These are not substances of abuse, but they're shockingly powerful to the point that you're not ready for the hero's journey for a long time. So these are not drugs of abuse by any stretch of the imagination. They really should be recategorized as a therapeutic drug.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

14. “I didn't thought of that. I'm not sure how to answer that. But I do think that once a new neurological pathways are established, you can capitalize on them by re-remembering them. And this is the thing that John Hopkins University, some of the most surprising results is 14 months after these experiences with many of the patients said it was the most important spiritual experience of their lives. 14 months afterwards, not only they have demonstrable benefits being nicer people, being a better parent, a better husband, socially more well adapted. But the fact that they re-remembered the experience reinforced those benefits that they experienced directly after the experience. So a lot of people, people who are listening may not understand these are not Of abuse. You eat these mushrooms one day, the next day you're like, No way.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

15. “Another good thing to tell a stutterer is, can you demonstrate different ways? They'll do it Want me to stutter different ways of stuttering? I'll give you three different ways of stuttering, and so it's really weird.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

16. “Now, this is where even I, and I'm a liberal kind of guy, I'm going, wait a second, you know. Tell me that again, you know, and that's why Bill set me up by saying you have to tell other people this. So I've been working with you with Roland Griffiths at Johns Hopkins University, the clinical studies on psilocybin, et cetera. And I really emphasize this to many of the researchers, they could easily do a test. Why these patients are in session to test their hearing to see if they have increased sensitivity, increased range, tonal ranges is a very easy metric. But I think what happened with me on the tree in the lightning storm is that I created a new neurological pathway of articulating my thoughts and overcoming the phobia. The social phobia is a trigger. It's definitely an environmental trigger. And then we get locked into these loops that are really, really strange.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

17. “The hero's journey. I was, you know, took out my hearing aid. I'm laying in full bliss, one with the universe. He's like 80 years age or 82 years of age when he's doing this by himself. And he said, no, I could hear the seagulls. I could hear the waves. I go, oh my gosh, I could hear everything. And he reached for his hearing aid and he didn't have it in. He goes, oh my gosh, I can hear. And then he heard this click, click, click, click. Tap, tap, tap, tap, tap. He looked around going, that's that's weird. That's an unusual sound. And click, click, click, click, tap, tap, tap, tap, tap, click, click, and he goes, he couldn't figure out what it was. He looked around and looked around, and finally he saw what it was. There are ants walking on the deck, and he was hearing their footsteps.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

18. “And Bill calls me up about three or four months before he dies. And he goes, Paul, I have to tell you something that's so important. And Bill says, I haven't heard from you in years. How's it going? He goes, well, frankly, life sucks. I've lost losing my sight. I'm losing my hearing. I can't hear the waves or the sequels now. I live above the cliffs of Big Sir, except for this damn hearing aid, which is always malfunctioning. I've got to tell you something that's so important that you know. And I go, okay, Bill. And I said, when is it? And Bill goes, no, I really want you to listen, Paul. This is important. I go, Bill, I understand. And then he kind of kept on emphasizing it. And finally, I got frustrated. I said, Bill, I got the message. Okay. I know what you're going to tell me is important. He goes, I want to make sure that you tell other people, will you promise me? And I go, I promise you. I said, Paul, I think I found something medically very important about psulmon. I go, what? I said,”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

19. “So Bill and I became tight friends, invited me down to Big Sur. He was a friend of Henry Miller and just a really fantastic individual. He became a father figure to me at a really critical time in my life. And so Bill and I did journeys together, sacred journeys. And he led my Obi-Wan Kenobi. You realize I'm 19, 20 years of age. I'm with a 75-year-old, you know, who's a friend of Ansel Adams. He had Ansel Adams library of many of his imprints and working with his wife. I mean, really cultured, intellectually interesting guy. Beautiful place. And so Bill and I tripped several times. And it was a wonderful experience for me. And it brings tears to my eyes just talking about Bill. He died about 15 years ago.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

20. “And so I made an appointment. I go up to Seattle and I've been meeting the head of Montana Books. And he goes, You know, this is not our market. This is an interesting subject. Really what you need is a book agent that goes, the best book agent I know is Bill Webb and I haven't seen him in two years. And at the sounds of those words, a little bell jingles on the front door of Montana Books and in walks Bill Webb and the publisher went, no way.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

21. “Friend is passed on now named Bill Webb. He's lived in Big Sur, California. And I was 19 years old when I wrote my first book, Silosophy Mushrooms and their Allies. I was self-trained. I got involved in the University of Washington with Dr. Daniel Stunt, part of a taxonomic key council, and I adopted the taxonomy of psilocybin mushrooms as my speciality. At that time, there's very little literature on it. Most of the books and libraries have been razored. The pages have been razored out. Dr. students had an intact library, so I could study with them. I became a taxonomist. I wrote taxonomic keys starting when I was 19 or 20, and that became the core of my book. I have this manuscript and I go to Montana Books in Seattle to pitch the book. And Montana Books is releasing some gay-friendly literature, and they're on the cutting edge. And it was recommended that I see that.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

22. “And she's coming along the sidewalk in the morning and she looks at me and she's so sweet. She says, good morning, Paul. How are you? And I cast my eyes up from the sidewalk and I looked at her and I said, I'm doing fine. Thank you for asking. And I stopped stuttering just like that. Now, I do have, I've had about four or five relapses. If it's a lot of noise and I've been drinking and somebody asked me, how do you grow mushrooms? It's like filling a well with a teaspoon, like, where do I begin? Or if I'm meeting somebody super famous or something like that, you know, but that's natural. People get stage fright when they're, you know, so, but it's something that I think is really important because there's one other aspect that's related to hearing that I want to mention. And I have a really good friend.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

23. “Look at them, smile, and engage, help them finish their sentence, don't finish it for them. That robs them of the opportunity of overcoming this speech deficit. So I scored high in my test. I felt like I had achieved a state of Godhead. I felt enlightened. I come from a Christian background. So I had this empathy with Jesus, you know, and now you understand why Jesus went in the wilderness. Now I understand why Jesus, you know, said, don't go into churches, go in the nature, or whatever. That's my cultural background. But I saw I connected on that level and I realized, oh my gosh, this is something I can overcome. So I came out of the tree, obviously did not get electrocuted. And I went back home. And then the next morning there's this girl that I greatly admired. And she was super sweet and nice to me. And I really love her to this day because of her kindness. And I didn't want to talk to her because every time I, you know, then you get these half breaths going on and then you can't get out of this loop.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

24. “Of existence. And then the light used to warm on. The wind came up and washed with warm rain. It was just terrifying a lightning storm. And I'm up there and I'm thinking, oh, I'm going to die. But if I don't die, Paul, what are you going to learn from this experience? Challenge yourself right now. This is all great and wonderful, but let's get down to brass tacks. What's your biggest issues? You're not going to die. What's your biggest issue? Stuttering. So I'm having this dialogue for myself. I just can't overcome the stuttering habit. You know, I'm not stupid. And I went to where people to understand how bad it was, I was interviewed for special education because of my stuttering because I couldn't read in class. And so when it was my turn to read, they would pass on me because no one had the patience to hear a stutterer. And please don't finish the stutterer sentence.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

25. “It's a rather aerial night. He got the Nobel Prize for it in 1955. But that was a deep dive into inner space exploration. But I felt like I was part of the glass bead game. And there I was. I was ascending into this higher state of consciousness. And then I realized, oh my God, I'm in the highest point in miles doing a lightning storm. This is not a good place to be. And then I was up there, I was terrified and the lightning storm came closer and closer and I had these empathogenic, just empathy for the universe. One, everything is fine. If I die here today, my life is complete. Now I understand I'm part of the fabric of all the matter that's around me. I'm one with everything. I made of stardust. Everything's made of stardust. This is a continuum of nature. Death is natural. Birth is natural. Transitions are just the way.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

26. “Really quickly, and I'm getting higher and higher as a thunderstorm, lightning storm is coming closer and closer. I'm getting vertigo, and I go, oh my God, I can't get off the tree. I don't want to fall. So I held on the tree for dear life, and it became my Axis Mundi, sort of my axis right into the earth. And I had this amazing experience. I mean, just beautiful experience, but also the threat of lightning coming closer and closer. And every lightning strike, it would hit and be fractal patterns would just emanate out from every lightning strike. And synesthesia occurred, you know, where sound and visions were merging together and sounds had visions and visions had sounds. And it was just incredibly complex. One of my favorite books of the glass bead game by Herman Hessse, also called Matter Ludi.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

27. “And this tree had his limbs, so it was a perfect climbing tree, and at the very top of a hill. So that's a great place. I mean, set and setting, getting a good view, that's what I need. And I could feel the mushrooms coming on. As I climbed up the tree, stem branch by branch, I got higher and higher. So it was kind of this ascending euphoria that kind of went with everything. It was very cool. And I got to the top of the tree and beautiful landscape. I'm up there and just the mushrooms are coming on. I'm getting higher and higher. And I realized I'm really getting high here in this little dizzying. So I'm holding on to the tree. And on the horizon with this big black bank of boiling dark, angry clouds, it was a summer storm coming in. In Ohio, when you see the summer storms, they're terrifying. Lightning bolts coming down and thunder and lightning. There's often the distance, but it's coming down to me.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

28. “Now, in defense of this, I need to make it clear, these were not grown. These were harvested. And so they were exposed to the sun. So they may have been only the equivalent to like 10 grams of kubensis. For people who are listening 5 grams of philosophy cubensis to the hero's journey, you're a full-blown. You're into Starscape. You're changing dimensions. fractal patterns, the air becomes a sea of mathematical formulas and your mind is opened up, your heart's opened up, you feel one with the universe. That's the hero's journey. That's five grams. You really don't get that until going over three grams. You start to get into it. So 10 to 20 grams is the superhero's journey. I've never eaten these before. So I walked, I was walking into this place about an hour walk. I started consuming them and drinking water because they were dried. And then I saw a tree that I love climbing.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

29. “14, 15 years of age. I mean, drugs on display. Drugs you've heard about, you've never seen How small that LSE is. That's incredible. So I still had this really bad stuttering habit and it was really socially debilitating on multiple levels. And so I ended up, and I was in Ohio buying a bag of magic mushrooms. I don't know if I know how things should cost, you know. For 20 bucks, I bought a bag. And I knew set and setting was really important, but I had no guide, nobody else in my little circle was into it. And so there was a really great walk that I would like to walk in the woods up on the hills and beautiful rolling hills of Ohio, northern Ohio. And I thought, okay, satin setting's important. So I took the bag and I thought that would be one dose. Was not one of those folks. I probably ate about 20 grams. Oh my.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

30. “Medical school on full scholarship, and I was left in the laboratory, and so I started experimenting with marijuana. I remember when the DEA came to the Columbia and Ohio, they had a whole display of drugs and a whole bunch of me and my friends just went there to look at them. Wow, look at that one.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

31. “What? He goes, yeah, it was sooner to be counterculture and threatening to our family structure. I go, I could not believe it. I was so upset. I was so apologetic to my brother who did not take it well. Last time I'm going to trust you. So I was really bad. But I thought to myself, you know, if this was so disturbing to this alpha male conservative neocon-like personality, then I think I found a subject I want to explore more. So that got me into magic mushrooms. And from my experience and also a tremendous amount of guilt for my brother trusting me with his textbook and I couldn't return it to him. So John was really interested in the subject. He inspired me. And then John went on to chemistry, then neurophysiology, University of Washington, Medicine.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

32. “Yeah. So I go, where's my book? And where are my brother's book? And then two weeks and brother John's now pressuring me. So I finally got a hold of Ryan and I said, Where is my brother's book? And Ryan said, Paul, I can't give it back to you. And I said, why? My dad found it and burned it. I said your dad burned my brother's book.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

33. “See it, but he says, Well, listen, I'm on break for two weeks, but I need the book because part of our class. So I got this book. I'm just devouring this book. And John was my hero. He was my mentor. And John went to Mexico and Colombia, came back with incredible stories of magic mushrooms and consuming them. You know, I just adored him. And of course, I wanted to do the same. Then he gave me this book. And so I'm really getting excited about this. My best friend, Ryan Snyder, wanted also to read this book. And so Ryan goes, can I borrow your book? Your brother's book. I goes, sure, you can borrow it, but I need it back. And so give it back to me in two or three days. So several days passed and asked Ryan about the book and he hemmed in hot. And a week later, where's the book? And he wouldn't respond, sort of look at me in the eye.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

34. “Huge, like three racks of chemicals, you know, in the basement and this laboratory. He had Bunsen burnerers, all sorts of experiments going all the time. But he never let me quote-unquote play in the laboratory. I could play on the radio and I could watch him. But he's my older brother. I was a youngest one of my family. And so John went on to Yale. My brother Bill went on to Cornell. And they left me in this laboratory. So my dream was always to have a laboratory living in the country. And that's kind of what I'm doing now. But John, when he came back from Yale, came back with a book called Altered States of Consciousness by Charles Tart. And it was an anthology of research articles on changing your consciousness from either drugs or from spinning or from dreams. One of the early books from University of California Davis. So John lent me this book and I said, Johnny, I'd never like this.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

35. “We don't stutter if I stop speaking in a British accent or you create an accent and you don't stutter when you talk to animals. So it's a very interesting that's triggered by social contact. And so it was very difficult for me to date ladies. They wanted the super jocks, the self-assured men. And I was a stutterer. And so I always stared at the ground and I found fossils. I found mushrooms. But it's very difficult for me. Now, I grew up in a small town in Ohio, and my dad was an officer on the aircraft carrier of the intrepid. And so during World War II. So after World War II, he got the intrepid aircraft carrier radio and was in our basement. And so my brother John, he was very interested in chemistry. He created this huge, you know.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

36. “But I started stuttering when really when I was about five years old, I mean, I started from the time that I could talk. My family was dysfunctional. And I've been told that sometimes the type of stuttering that I have is related to a defect, a neurological development in the seventh and eighth month. That's one possible reason. But the type of stuttering I have, anyone seen the king's speech, I had that and worse. So I, you know, just could not speak. And I'd find alternative pathways to trick my brain with a prepositional or adverbial phrase because your brain gets further ahead in your mouth, can articulate. And then you become self-conscious. And the type of stutterer that I am, as most stutterers, we don't stutter when we say.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

37. “Sustainable solution based on nature. And they looked at her in a dour face. And then the chairman of the company looked at her and said, Chris, your budget never was in research. It was in advertising. Very much similar to BP. Remember, beyond petroleum? How much of a BP's budget actually is an alternative fuels versus how much is in oil? Now, how much is their advertising budget is in alternative fuels as opposed to oil? I mean, clearly, it's called greenwashing. And so that happened like seven or eight years ago, and then just past month I just had the same thing happen again. It's a disruptive technology. It rocks the Apple cart and many of these insecticides are coming from the petroleum industry as byproducts from their waste material”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

38. “Connected, went over the data together, messaging how to create the most clear communication to the board of directors, all men. And she was a steel magnolia. I've never met her in person. I wanted to hire her immediately. She ran these meetings just so professionally. And she was really excited. And she goes in. The next day in the afternoon, I'm waiting for her call. And she calls. And the person on the phone is so angry. I'm going, who is this? And I go, this is Chris. She goes, I'm so angry I can't see straight. I go, I mean, she's totally composed before and she's lost her composure. I go, Chris, what happened? She goes, I went in there, I made my presentation. All men, they looked at me steely-eyed, and she said, this is the best, you gave me this mandate. I found something. This is a game changer. We can come with an ecologically rational.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

39. “I have one really great story on this woman named Chris that works for a company that has three letters in their name. She was given the mandate because their stockholders were really upset because of the reputation of this company causing toxic spills that harmed thousands of people. And they wanted to grow green movement. Can you find green solutions? She was given the mandate to find a green solution to replace toxic insecticides. She was given a budget. She found me. We dialogued for months. I gave her samples. She set up experiments to the researchers who were so excited. They called me up at home. And both of them said, I'm not supposed to be telling you this, but this is the most exciting thing we've ever seen in our life as entomologists in fighting these problems. She went to the board of directors prior to going.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

40. “Something that, because my aunts did not reinvade for 10 years, because after the ants were killed, the carpenter ants, they spoululated. So the spore repellency property prevented future invasions. That's not a very good economic model when you can treat a house once and they don't come back. A far better economic business plan is having consumer buying it every month and spraying toxic chemicals that kill the workers but don't kill the queen. The whole key to this is the mycelium is taken back into the nest like a Trojan horse. It's presented to the queen who then spreads it to the brood and they're all living in this honey, this sort of”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

41. “And I just submitted my entire portfolio with all my research and all eight or nine patents, all the documentation of all these companies that have done the research themselves. And I've submitted to a very, very well-known company that has an extremely potent insecticide that many people know that use it on the market. The word I got back is why would we want to disrupt a proven profit wheel”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

42. “Well, the test of a patent is that it's reproducible. The EPA and the USDA now are allowing this fungus in food handling facilities. The first fungus ever to be allowed for controlling insects in food handling facilities, it is that safe. The safety documents supplied by the EPA are now open sourced and in public domain. So the companies that did all the research proving that this fungus was not dangerous now have released all their commercial interest in it. The strain of metarisium called F52 is a public domain strain. So what I'm saying is you're not legal for you to go out and use this and commercialize it without EPA registration, but that test of the patent is reproducible. And so all of the methods for doing this is published.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

43. “And the third is usefulness. So those are the three things no prior art contrary to conventional wisdom and usefulness. And so obviously that fits all three of those categories. The pox molecules I have not patented. They're open source. Hopefully we'll never have a smallpox epidemic or pandemic again. And I think that's obviously serves a greater good.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

44. “As a long wait. The good news is approved in 2014, so I've got 17 years. And the whole thing about patents, I mean, we would not be talking today if there weren't patents. People think of, you know, patents become open sourced after 17 years. The idea is to reward the inventor, to incentivize things to come to market. Because a patent that is not practiced is not useful or beneficial to society within that 17 years or outside 17 years. It has to be brought to market. There has to be a commercial incentive. Patents are awarded for three reasons. One, no prior art, no evidence in the scientific or popular literature of anyone saying is having the same idea. Two, unobviousness. You want experts saying Paul Stamis, you're full of BS. This will never work. And so I have a message to all my critics out there. I want to say thank you. You have helped me so much in ways that you did not intend.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

45. “You're kidding. That's kind of a pat on my back. I was like, well, really, you think this is that important. But I said, that's not right. So we did an intergovernmental agency trace and a request. And the DOD finally released a patent to go back into the queue. And so 10 years after I submitted a patent application, folks usually two to three years you get a ruling, 10 years after I submitted the patent, it was approved.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

46. “A paradigm shifting solution that for many of the problems that we face today. But I filed this patent in 2004. 2006 is not even on the patent application homepage. Anybody out there who didn't know about patents, usually six months to a year, the patent application shows up at the USPTO.gov website, US patent and trademark office.gov website. And it didn't show up this over two years. So I caught a hold of my patent attorney going, you know, what is going on here? He gets a hold of the patent office and the Department of Defense took the patent out of the patent office because of national security.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

47. “Obviously, suddenly on their radar because I'm non-conventional, but the fact that I'm here today actually makes me more of a patriotic American than I was before. So anyhow, so I found these patents, a patent on a Garracon versus these viruses. I filed it in 2004. You can look this up, go to the US patent homepage. You'll see my filing dates. I filed this patent in 2004, 2009-11 was 2001. So I had to write the patent, get more research results. We got lots and lots of positive results from the BioShield program. I think I talked to one of the researchers last year, and he goes, do you know that we analyzed 2,392 of your samples? And I'm so glad I didn't have to pay for that. But we got about 40 excellent hits from my 800 or so cultures that were surprising, which has led into, I think.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

48. “And so I shut down the business. All the employees left, and the helicopter still buzzing around. And so the next day, I called up pretty pissed off to the colonel saying, what is going on? He got really nervous. Now he's got two black eyes, right? They delivered the wrong results to the wrong person. And now he goes, oh, the government, you know, one hand doesn't talk to the other and they got over-exuberant. If terrorists got this technology, they could immunize themselves and create a terrorist. It's like, whatever. So anyhow, it was funny because I was going through the airports. I got five stars on every single airline ticket. I joke to my wife, here we go again. I'm going to get stopped and search. And then after this, then all those five stars got taken away and I streamed through security, no problem.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

49. “Go, oh my God, you're kidding. I go, and this is right after we got the pox results, right after I talked to the colonel, like two weeks later or a week later. And I said, okay, listen, shut down the business. I knew immediately, you know, the government's going to screw up here and an abundance of caution. They're going to end up overstepping their bounds. And I said, this is crazy. I've already been vetted. I've already been permitted. I've already in dialogue.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT

50. “O my God I don't have to make up these stories. I don't have to make up any stories. They're too good to be true as they are. But this is what happened. I was in Canada. I'm speaking to you right now from Cortes, Ireland, British Columbia. I was up here on Cortez Island. And one of my employees called up and said, Paul, there's a helicopter buzzing around the laboratories. I go, no big deal. Helicopters fly over all the time. And he goes, no, it's really low. And I go, how low? And he goes, listen. He puts his cell phone up to the wow. I go, what are the numbers on the tail? He goes, there are no numbers. As a Black Hawk military helicopter that's right on top of the laboratories.”

    2018-10-11 · The Tim Ferriss Show · #340: Paul Stamets — How Mushrooms Can Save You and (Perhaps) the World · IDENTIFIED FROM THE TRANSCRIPT